实验动物与比较医学 ›› 2011, Vol. 31 ›› Issue (6): 473-477.DOI: 10.3969/j.issn.1674-5817.2011.06.018

• 综述 • 上一篇    下一篇

金黄色葡萄球菌感染动物模型的研究进展

杨玉琴1, 丁忆远3, 彭秀华1, 徐春华1, 周文江1,2   

  1. 1.上海市公共卫生临床中心, 上海201508;
    2.复旦大学药学院, 上海201203;
    3.陕西中医学院,陕西712046
  • 收稿日期:2010-11-15 修回日期:2011-09-30 出版日期:2011-12-25 发布日期:2011-12-25
  • 作者简介:杨玉琴(1980-),女,助理研究员,主要从事实验动物模型相关方面的研究,E-mail:fudanyan2007@sina.com

Research Progress on Establishment of Animal Model with Staphylococcus aureus Infection

YANG Yu-qin1, DING Yi-yuan3, PENG Xiu-hua1, XUN Chun-hua1, ZHOU Wen-jiang1,2   

  1. 1. Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China;
    2. Pharmacy College of Fudan University, Shanghai 201203, China;
    3. Shanxi Institute of Traditional Chinese Medicine, Shanxi 712046, China
  • Received:2010-11-15 Revised:2011-09-30 Online:2011-12-25 Published:2011-12-25

摘要: 总结通过不同途径建立金黄色葡萄球菌感染的各种动物模型的方法、机理、合适动物、灵敏指标及在药效学评价中的应用现状,为制备更简便、经济且与临床更接近的金黄色葡萄球菌感染动物模型提供文献依据和研究思路。

关键词: 动物模型, 金黄色葡萄球菌, 感染

Abstract: The purpose of the review was to summary the infection methods, mechanism, the suitable animals, sensitive indicators in establishment of Staphylococcus aureus (SA), and the present situation of the application in pharmacodynamics evaluation .It may be provides the literature and ideas for building SA infection animal model which is simpler, more economical and closer to clinical human SA infection.

Key words: Animal model, Staphylococcus aureus, Infection

中图分类号: