实验动物与比较医学 ›› 2011, Vol. 31 ›› Issue (5): 399-403.DOI: 10.3969/j.issn.1674-5817.2011.05.021

• 综述 • 上一篇    

轮状病毒感染小鼠模型研究进展

杨蒙蒙1, 张琰1, 刘新友1, 罗佳波2   

  1. 1.第四军医大学唐都医院药学部,西安 710038;
    2.南方医科大学中医药学院中药新药实验室, 广州 510515
  • 收稿日期:2010-12-22 出版日期:2011-10-15 发布日期:2011-10-25
  • 作者简介:杨蒙蒙(1980-),女,博士,主管药师,研究方向:中药学与医院药学,E-mail:ymengmeng1980@163.com

Progress on Study of Rotavirus Mouse Model

YANG Meng-meng1, ZHANG Yan1, LIU Xin-you1, LUO Jia-bo2   

  1. 1. Pharmaceutics Department of Tangdu Hospital of the Fourth Military Medical University, Xi’an 710038, China;
    2. New Chinese Traditional Herbs Laboratory of Traditional Chinese Medicine Institute of Southern Medical University, Guangzhou, 510515, China
  • Received:2010-12-22 Online:2011-10-15 Published:2011-10-25

摘要: 综述轮状病毒感染小鼠模型首次建立以来的研究概况。对同源性轮状病毒(即鼠源病毒)和异源性轮状病毒感染小鼠在体内病毒复制、临床表现及病理改变以其病理生理机制等方面的不同特点进行比较分析、总结。

关键词: 轮状病毒, 小鼠, 模型, 综述

Abstract: To summarize the study progress of rotavirus infected mouse model by analyzing the difference of virus replication, clinical performance, pathology change and pathophysiological mechanism between mice infected with homologous and heterogeneous virus.

Key words: Rotavirus, Mice, Model, Review

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