关键词: 猕猴, 血液学, 心肺功能, 生理指标

Abstract: Objectives To detect the physiological parameters of juvenile rhesus monkeys. Method One hundred healthy 3 to 4-year-old juvenile rhesus monkeys (♂50, ♀50)were measured for a comprehensive examination about their hematological, cardiopulmonary function and other physiological parameters, including 30 routine blood tests, 22 blood biochemical indexes, 2 blood coagulation tests as well as blood pressure, electrocardiogram and respiratory rate. Result Mean corpuscular hemoglobin concentration (MCHC) (P<0.01) in the female rhesus monkeys was significantly lower than that of male monkeys; whereas platelet count (PLT), thrombocytocrit (PCT), eosinophil(EO), basophilic granulocyte (BASO), EO percentage (%), BASO percentage(%) (P<0.01) and white blood cell count (WBC), lymphocyte count (LYMPH) (P<0.05) were significantly higher in females juvenile rhesus monkeys than those of males. For the blood biochemical parameters,urea nitrogen (BUN), total bilirubin (TBIL), γ-glutamyl transpeptidase (γ-GTP), inorganic phosphorus (IP) (P<0.01) and glutamic-oxalacetic transaminease (AST), albumin (ALB), bilirubin (Total & Direct) (DBIL) (P<0.05) was significantly lower in the female than in male; while glucose (GLU),calcium (Ca) and triglycercide (TG) was significantly higher in females than in males (P<0.05). There were no significant differences in parameters considering blood coagulation tests,blood pressure and electrocardiogram between male and female juvenile rhesus monkeys. Respiratory rate was significantly reduced in female than in male (P<0.01). Conclusion The physiological biochemical parameters in experimental juvenile rhesus monkeys which might provide basis for reference values for animal experiments and disease diagnosis using juvenile rhesus monkeys.

Key words: Rhesus monkeys, Hematology, Cardiopulmonary function, Physiological parameters