单笼与群居饲养对雌性食蟹猴生理指标的影响

doi:10.3969/j.issn.1674-5817.2016.05.009

实验动物与比较医学 ›› 2016, Vol. 36 ›› Issue (5): 369-373.DOI: 10.3969/j.issn.1674-5817.2016.05.009

所属专题：实验动物设施设备；实验动物资源开发与利用

单笼与群居饲养对雌性食蟹猴生理指标的影响

李伟^1,2, 金益^1,2, 柏熊^1,2, 王晓东^1,2, 邢正弘^1,2, 王校权³

1.上海西普尔-必凯实验动物有限公司, 上海 201203;
2.上海实验动物研究中心, 上海 201203;
3.上海本庄生物科技有限公司, 上海 201403

收稿日期:2016-02-18 出版日期:2016-10-25 发布日期:2016-10-25
作者简介:李伟(1980-),男,助理研究员。E-mail: tianshixz@126.com
基金资助:
上海市科委实验动物研究专项(13140901200)

Comparison on Effects of Single Caged and Social Group on Physiological Indexes of Female Macaca Fascicularis

LI Wei^1,2, JIN Yi^1,2, BAI Xiong^1,2, WANG Xiao-dong^1,2, XING Zheng-hong^1,2, WANG Xiao-quan³

1. Sino-British SIPPR/BK Laboratory Animal LTD., Co, Shanghai 201203, China;
2. Shanghai Laboratory Animal Research Center,Shanghai 201203, China;
3. Shanghai Benzhuang Bioscience LTD., Co, Shnaghai 201403, China

Received:2016-02-18 Online:2016-10-25 Published:2016-10-25

摘要/Abstract

摘要： 目的了解单笼与群居饲养雌性食蟹猴生理指标的差异。方法选取9只4~6岁雌性食蟹猴作为实验对象,前5个月单笼饲养,后5个月群居饲养。对体质量、体温、血常规、血生化、尿常规等生理指标进行测定。采用重复测量方差分析比较两阶段指标是否存在差异。结果食蟹猴单笼阶段的体质量显著低于群居阶段(P<0.05)。血常规中,单笼阶段的白细胞计数(WBC)、嗜中性粒细胞计数(NEUT)、嗜中性粒细胞百分比(NEUT%)极显著高于群居阶段(P<0.01); 单笼阶段的单核细胞计数(MONO)、单核细胞百分比(MONO%)极显著低于群居阶段(P<0.01); 单笼阶段的淋巴细胞百分比(LYMPH%)显著低于群居阶段(P<0.05)。血液生化中,单笼阶段的总胆红素(TBIL)极显著低于群居阶段(P<0.01); 单笼阶段的天门冬氨酸氨基转移酶(AST)、甘油三酯(TG)显著高于群居阶段(P<0.05)。单笼阶段的尿常规中的蛋白质阳性率高于群居阶段,组间相比差异显著(P<0.05)。其余指标组间相比无统计学差异。结论食蟹猴更适合群居饲养,如果长期单笼饲养,可能对其体质量及血液学和尿常规中某些指标产生较大影响。

关键词: 食蟹猴, 雌性, 生理指标, 血液学, 尿常规

Abstract: Objective To understand the differences on physiological indexes of single caged and social group female macaca fascicularis. Methods Nine female cynomolgus monkeys at the age of 4-6 years old were singly raised in cage at the first 5 months,and group raised in next 5 months.The body weight, body temperature, blood routine, urine routine, blood biochemistry were measured in single caged rearing and group breeding, repeated measures analysis of variance was used to compare whether there were differences between the two stages. Results Body weight in single caged stage was significantly lower than that in group phase (P<0.05). In blood routine, white blood cell count (WBC), neutrophil count (NEUT), neutrophil percentage (NEUT%) in single caged stage were significantly higher than that in group stage (P<0.01); monocyte count (MONO), the percentage of mononuclear cells (MONO%) in single caged stage were significantly lower than that in group stage (P<0.01); lymphocyte percentage(LYMPH%) in single caged stage was significantly lower than that in group stage (P<0.05). In blood biochemistry, total bilirubin(TBIL) in single caged stage was significantly lower than that in group stage (P<0.01); aspartic acid amino transferase (AST), triglyceride (TG) in single caged stage were significantly higher than that in group stage (P<0.05). The positive rate of urine protein in single caged stage is higher than that in the group stage(P<0.05). Other indexes between the groups had no statistical difference. Conclusion The macaca fascicularis was more suitable for the breeding of group, if the long-term single caged feeding, it could have a greater impact on body weight, hematology and urine routine of some indicators.

Key words: Macaca fascicularis, Female, Physiological index, Hematology, Urine routine

中图分类号:

Q95-33

李伟, 金益, 柏熊, 王晓东, 邢正弘, 王校权. 单笼与群居饲养对雌性食蟹猴生理指标的影响[J]. 实验动物与比较医学, 2016, 36(5): 369-373.

LI Wei, JIN Yi, BAI Xiong, WANG Xiao-dong, XING Zheng-hong, WANG Xiao-quan. Comparison on Effects of Single Caged and Social Group on Physiological Indexes of Female Macaca Fascicularis[J]. Laboratory Animal and Comparative Medicine, 2016, 36(5): 369-373.

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单笼与群居饲养对雌性食蟹猴生理指标的影响

Comparison on Effects of Single Caged and Social Group on Physiological Indexes of Female Macaca Fascicularis

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