实验动物与比较医学 ›› 2016, Vol. 36 ›› Issue (1): 37-40.DOI: 10.3969/j.issn.1674-5817.2016.01.007

所属专题: 实验动物资源开发与利用

• 论著 • 上一篇    下一篇

不同日龄新西兰白兔血液学特性研究

恽时锋, 董敏, 赵志刚, 陈莉, 刘彪, 田小芸   

  1. 南京军区南京总医院比较医学科,全军实验动物科普与伦理教育基地,全国科普教育基地,南京 210002
  • 收稿日期:2015-06-30 出版日期:2016-02-25 发布日期:2016-02-25
  • 作者简介:恽时锋(1965- ), 男, 教授, 从事实验动物管理工作。E-mail: yunshifeng1@163.com

Experimental Study on Hematological Parameters of New Zealand White Rabbits at Different Ages

YUN Shi-feng, DONG Min, ZHAO Zhi-gang, CHEN Li, LIU Biao, TIAN Xiao-yun   

  1. Department of Comparative Medicine, Nanjing General Hospital of Nanjing Military Command, Army Education Base of Science and Ethics of Experimental Animal, National Science Education Base, Nanjing 210002, China
  • Received:2015-06-30 Online:2016-02-25 Published:2016-02-25

摘要: 目的 探讨不同日龄封闭群新西兰白兔的血液学特性。方法 采集不同年龄、不同性别新西兰白兔的血液样品,应用全自动血细胞仪测定160只新西兰白兔的血液学指标。结果 各年龄段新西兰白兔血液学指标性别间无显著差异(P>0.05),不同年龄段之间除单核细胞总数差异不显著(P>0.05),其它指标有显著差异(P<0.05)。结论 本院培育自繁的实验型封闭群新西兰白兔生物学特性较稳定,个体间差异较小,初步建立了不同日龄新西兰白兔血液生理指标正常值,为新西兰白兔的广泛使用提供基础数据。

关键词: 新西兰白兔, 各年龄段, 血液学特性

Abstract: Objective To investigate the hematological parameters of outbred colony New Zealand white rabbits at different ages. Methods Blood samples from 160 New Zealand white rabbits (Female, 80 and male, 80) in different age groups were analyzed with automatic blood cell analyzer. Result There was no statically significant difference between the blood samples of different age experimental closed colony New Zealand white rabbits in different sex sets (P>0.05). Significant differences (P<0.05) of hematological indexes except monocyte (P>0.05) were observed among New Zealand white rabbits in different age groups. Conclusion The outbred colony New Zealand white rabbits had stable biological characteristics and less difference among individuals. In this study, the biological hematologic parameters database for New Zealand white rabbits at different ages was established, which will be used as basic reference for New Zealand white rabbits experiment.

Key words: New Zealand white rabbits, Different ages, Hematological parameters

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