实验动物与比较医学 ›› 2011, Vol. 31 ›› Issue (5): 384-388.DOI: 10.3969/j.issn.1674-5817.2011.05.018

所属专题: 实验动物资源开发与利用

• 论著 • 上一篇    下一篇

黑线毛足仓鼠实验动物化及部分生物学特性观察

黄珍祯, 赵源, 樊海艇, 汤家铭   

  1. 上海中医药大学实验动物中心, 上海201203
  • 收稿日期:2011-01-18 出版日期:2011-10-15 发布日期:2011-10-25
  • 作者简介:黄珍祯(1988-),女,实验员。研究方向:实验动物育种,E-mail:usual_1988@126.com
  • 基金资助:
    科技部《重大新药创制基金》(上海中医药大学2009ZX09502-002)

Studies on Black Line Hamster (Phodopus sungorus) Used for Research and Their Biological Characteristics

HUANG Zhen-zhen, ZHAO Yuan, FAN Hai-ting, TANG Jia-ming   

  1. Laboratory Animal Center, Shanghai University of Traditional Chinese Medicine , Shanghai 201203, China
  • Received:2011-01-18 Online:2011-10-15 Published:2011-10-25

摘要: 目的 将宠物黑线毛足仓鼠实验动物化,扩大实验仓鼠的种质资源。方法 按啮齿动物分类鉴别方法鉴定属种; 按照实验动物标准化要求进行人工繁育,观察个体生长发育、繁殖、解剖学特点,称重测定主要脏器、检测血液学和血液生化学指标。结果 经外形、头骨测定和染色体检查,符合仓鼠亚科毛足属的黑线毛足仓鼠的特征。黑线毛足仓鼠在普通级环境中饲喂全价营养颗粒饲料能长期同居繁殖,生长发育良好。血液学和血液生化学检测除少数指标外,两性间差异无显著意义。结论 经过人工繁育和标准化,黑线毛足仓鼠已初步达到实验动物化。生长发育、繁殖的观察和主要脏器称重、血液学和血液生化学指标检测为其在生物医学研究领域里的应用提供参考。

关键词: 黑线毛足仓鼠, 实验动物, 生物学特性

Abstract: Objective To raise the pet black line hamsters(Phodopus sungorus) for research use according to the standard breeding practise of laboratory animals, thus to expand the experimental hamster species resources, and fulfill the needs of biomedical researches. Methods The species was identified according to the rodents classification and identification methods. The animal was bred according to laboratory animal standardization requirements. The growth, development, reproduction, anatomical features were observed. The main viscera weight, hematology and blood biochemistry normal values were determined. Results The species is in accordance with the black line hamster (Phodopus sungorus)characteristic of hamsters subfamily by examination of the appearance, skull determination and chromosome check. The black line hamsters grow well in conventional environment with full nutrition granule feeds, and can be long-term male-female paired and bred. Hematology and blood biochemistry detection showed no significant differences between the sexes except a few indexes. Conclusion After breeding and standardizations, the black line hamster can be used for experiment. The observation indexes of the growth and breeding, and the determination of main viscera weighing, hematology and blood biochemistry normal values provide the reference for its biomedical research use.

Key words: Black line hamster (Phodopus sungorus), Laboratory animal, Biological characteristics

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