实验动物与比较医学 ›› 2022, Vol. 42 ›› Issue (2): 95-101.DOI: 10.12300/j.issn.1674-5817.2021.164

所属专题: 实验动物设施设备

• 实验动物与生物安全专题 • 上一篇    下一篇

实验动物屏障设施管理中面临的生物安全问题及对策探讨

杨玉琴()()   

  1. 上海市第一人民医院实验动物中心, 上海 200080
  • 收稿日期:2021-10-25 修回日期:2021-12-10 出版日期:2022-04-25 发布日期:2022-05-07
  • 作者简介:杨玉琴(1980—), 女, 硕士。主要从事实验动物管理及动物实验研究。E-mail:fudanyan2007@sina.com
  • 基金资助:
    上海市科学技术委员会资助科技计划项目(201409002300)

Biosafety Problems and Countermeasures in the Management of Barrier Facilities for Laboratory Animals

Yuqin YANG()()   

  1. Department of Laboratory Animal Center, Shanghai General Hospital, Shanghai 200080, China
  • Received:2021-10-25 Revised:2021-12-10 Online:2022-04-25 Published:2022-05-07
  • Contact: YANG Yuqin, E-mail: fudanyan2007@sina.com

摘要:

生物安全是国家安全的重要组成部分,有效控制实验动物生物危害是使用实验动物的基础。本文从实验动物设施管理者的角度,以上海市第一人民医院实验动物中心的生物安全管理经验为基础,分析了目前实验动物屏障设施在保证动物实验顺利开展过程中所面临的潜在生物安全威胁,并探讨了降低此类风险的相关对策,以期为良好控制动物实验中生物安全问题提供借鉴。

关键词: 实验动物, 生物安全, 设施管理, 问题与对策

Abstract:

Biosafety is an important part of national security, and effective control of biological hazards of laboratory animals is the basis of using laboratory animals. Based on the experience of biosafety management in the Laboratory Animal Center of Shanghai General Hospital, this paper analyzed the potential biosafety threats faced by laboratory animal barrier facilities in the process of ensuring the smooth conducting of animal experiments from the perspective of a laboratory animal facility manager, and discussed the relevant countermeasures to reduce such risks, in order to provide a reference for the proper control of biosafety problems in animal experiments.

Key words: Laboratory animals, Biosafety, Facility management, Problems and countermeasures

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