疼痛抑郁共病动物模型及评价方法研究进展

doi:10.12300/j.issn.1674-5817.2021.097

摘要/Abstract

摘要：

慢性疼痛伴发抑郁症状是常见的健康问题，严重危害了患者的身心健康，但这些症状的发生机制仍不清楚。为全面了解疼痛抑郁共病的发生机制及其治疗方法，疼痛抑郁共病动物模型的建立至关重要。本文就目前国内外疼痛抑郁共病相关的动物模型建立及行为学评价方法进行综述。

关键词: 疼痛共病, 抑郁症, 动物模型, 评价方法

Abstract:

Comorbidity of pain and depression is a common health problem that seriously affects the physical and psychological health of patients. However, the pathogenesis of these symptoms remains unclear. To comprehensively understand the mechanisms and treatments of pain and depression comorbidity, this review summarizes the establishment of related animal models and behavioral evaluation methods of pain and depression comorbidity at home and abroad.

Key words: Comorbid pain, Depression, Animal model, Evaluation

中图分类号:

Q95-33

何仁可,鲁程,陈薇,等. 疼痛抑郁共病动物模型及评价方法研究进展[J]. 实验动物与比较医学, 2022, 42(1): 68-73. DOI: 10.12300/j.issn.1674-5817.2021.097.

Renke HE,Cheng LU,Wei CHEN,et al. Advances in Animal Models and Evaluation Methods of Pain and Depression Comorbidity[J]. Laboratory Animal and Comparative Medicine, 2022, 42(1): 68-73. DOI: 10.12300/j.issn.1674-5817.2021.097.

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