基于VOSviewer的中医护理技术动物实验可视化分析

doi:10.12300/j.issn.1674-5817.2023.037

实验动物与比较医学 ›› 2023, Vol. 43 ›› Issue (6): 626-635.DOI: 10.12300/j.issn.1674-5817.2023.037

基于VOSviewer的中医护理技术动物实验可视化分析

苗金环¹, 徐霞²()(), 周璐¹, 成海燕¹, 何燕¹

^1.甘肃中医药大学护理学院, 兰州 730030
^2.甘肃省中医院临床教学部, 兰州 730050

收稿日期:2023-03-29 修回日期:2023-08-08 出版日期:2023-12-25 发布日期:2024-01-06
通讯作者: 徐霞（1977—），女，硕士，研究员，研究方向：循证护理学、护理管理、中医护理及卫生事业管理。E-mail: 540713843@qq.com。ORCID：0000-0001-7221-0443
作者简介:苗金环（1994—），女，硕士研究生，研究方向：中医护理。E-mail： 793233083@qq.com
基金资助:
国家自然科学基金 “基于网络护理学中医药护理方案干预神经根型颈椎病的实验研究”(81960916)

Visual Analysis of Animal Experiments on Traditional Chinese Medicine (TCM) Nursing Technology Based on VOSviewer

Jinhuan MIAO¹, Xia XU²()(), Lu ZHOU¹, Haiyan CHENG¹, Yan HE¹

^1.School of Nursing, Gansu University of Traditional Chinese Medicine, Lanzhou 730030, China
^2.Clinical Teaching Department, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China

Received:2023-03-29 Revised:2023-08-08 Published:2023-12-25 Online:2024-01-06
Contact: XU Xia (ORCID:0000-0001-7221-0443), E-mail: 540713843@qq.com

摘要/Abstract

摘要：

目的通过对中医护理技术动物实验文献进行可视化分析，凝练相关研究热点，探讨相关动物模型的研究趋势，以期为后续研究提供参考。方法检索万方数据库（Wanfang）、维普（VIP）、中国知网（CNKI）、中国生物医学文献数据库（CBM）、PubMed、Web of Science自建库至2022年6月30日中医护理技术动物实验相关文献，用VOSviewer 1.6.17软件进行可视化分析。结果纳入1 864篇中文文献及126篇英文文献，年发文量逐年上升；相关文献涉及18项中医护理技术，其中涉及推拿的文献最多（426篇）；涉及4 496名作者，其中核心作者358名，占所有发文作者的7.9％；涉及3 706个关键词，形成7大聚类，研究热点主要有推拿治疗炎症性疾病及镇痛效应、穴位敷贴治疗哮喘相关呼吸道疾病、灸法治疗炎性疾病、穴位注射治疗变应性鼻炎和心肌缺血等；其中腹部推拿对胰岛素抵抗机制研究是最新研究主题。结论近年来中医护理技术动物实验研究中腹部推拿动物模型的热度持续上升，但是中药泡洗和中药热熨敷相关动物模型的建立和应用尚未引起重视，今后可在此领域探索，进一步完善我国中医护理技术动物实验研究。

关键词: VOSviewer, 中医护理技术, 动物实验, 可视化分析

Abstract:

Objective Through the visual analysis of animal experimental literature on Traditional Chinese Medicine (TCM) nursing technology, the relevant research hot spots were condensed and the research trends of relevant animal models were discussed, to provide reference for subsequent research. Methods The literature related to animal experiments on Chinese medicine nursing technology was retrieved from Wan Fang database, Chinese Science and Technology Journal Database (VIP), China National Knowledge Infrastructure Engineering Database (CNKI), China Biomedical Literature Database (CBM), PubMed and Web of Science until June 30, 2022. Visual analysis was performed using VOSviewer 1.6.17 software. Results A total of 1 864 articles in Chinese and 126 articles in English were included, with the number of annual publications increasing year by year. The relevant literature involved 18 TCM nursing techniques, with the largest number (426) involving massage having the highest number of articles. It involved 4 496 authors, out of whom 358 were core authors accounting for 7.9% of all authors, and had a total count of 3 706 keywords forming 7 clusters. The research hotspots mainly included massage treatment of inflammatory diseases and analgesic effect, acupoint injection treatment of allergic rhinitis and myocardial ischemia, acupoint application treatment of asthma-related respiratory diseases, and moxibustion treatment of inflammatory diseases. The study of the mechanism of abdominal massage on insulin resistance is the latest research topic among them. Conclusion In recent years, the animal model of abdominal massage has gained increasing popularity in animal experiments of TCM nursing techniques. However, the establishment and application of animal models related to Chinese medicine soaking and Chinese medicine hot ironing have not yet received attention. This area can be explored in the future to further improve the animal experimental research on Chinese medicine nursing technology.

Key words: VOSviewer, Traditional Chinese medicine nursing technology, Animal experiment, Visual analysis

中图分类号:

R-332

苗金环, 徐霞, 周璐, 成海燕, 何燕. 基于VOSviewer的中医护理技术动物实验可视化分析[J]. 实验动物与比较医学, 2023, 43(6): 626-635.

Jinhuan MIAO, Xia XU, Lu ZHOU, Haiyan CHENG, Yan HE. Visual Analysis of Animal Experiments on Traditional Chinese Medicine (TCM) Nursing Technology Based on VOSviewer[J]. Laboratory Animal and Comparative Medicine, 2023, 43(6): 626-635.

图/表 5

图1 中医护理技术相关动物实验的发文趋势图（A）、数量排名（B）及作者合作情况（C）注：A为中医护理技术相关动物实验的发文趋势图（蓝色数据线表示年度发文数量，橙色拟和线表示整体发文趋势。）；B为18项中医护理技术相关动物实验的文献数量排名；C为作者合作网络图谱（节点代表作者；连线表示作者合作情况，距离越近，作者间的合作就越频繁；相同的颜色代表同一集群）。

Figure 1 Trend chart (A), quantity ranking (B) and author cooperation status (C) of animal experiments related to medical and nursing technologyNote：A, Trend chart of literature publication in the TCM nursing technology animal experiment (The blue data line indicates the number of annual publications, and the orange line indicates the overall trend of publications). B, Ranking of animal experimental literature on 18 TCM nursing techniques. C, Author cooperation network diagram (Nodes represent the author; The line indicates the cooperation between authors. The closer the distance, the more frequent the cooperation between authors. The same color represents the same cluster).

表1 高频关键词

Table 1 High-frequency keywords

序号 Serial number	关键词 Keyword	频次 Frequency	共现次数 Number of co-occurrences
1	大鼠	184	219
2	穴位注射	182	155
3	推拿	129	104
4	艾灸	111	93
5	溃疡性结肠炎	104	85
6	麦粒灸	67	41
7	实验研究	55	68
8	动物模型	54	42
9	穴位敷贴	53	43
10	动物实验	47	49
11	足三里	40	54
12	类风湿性关节炎	40	45
13	推拿手法	40	22
14	灸法	37	58
15	哮喘	37	32

图2 关键词的共现标签视图（A）、密度视图（B）和时间趋势图（C）注：A为关键词共现标签视图（节点代表关键词，节点大小代表关键词的频次；相同颜色代表同一聚类；连线越粗，距离越近，关键词的联系越紧密）。B为关键词密度视图（图中颜色越接近黄色，表示该关键词密度越大，出现频次越高）。C为关键词时间趋势图（节点代表关键词；颜色由蓝色到黄色表示时间由远及近）。

Figure 2 Co-occurrence label view（A）， density view（B） and time trend diagram （C） of the keywordsNote：A is keyword co-occurrence tag view (each node represents a keyword, with node size indicating frequency; nodes of the same color belong to the same cluster; thicker lines indicate closer connections between keywords). B is the keyword density view (the closer the color is to yellow in the figure, the higher the keyword density and the higher the frequency of occurrence). C is time trend diagram of keywords (nodes represent keywords; the color from blue to yellow indicates the time from far to near).

表2 中医护理技术动物实验文献关键词聚类及研究主题

Table 2 Keyword clustering and research topics in the animal experimental literature of TCM nursing technology

聚类ID Cluster ID	关键词数量 Number of keywords	研究主题 Research topic	主要关键词 Main keywords
#1红色 #1 Red	13	推拿治疗炎症性疾病及镇痛效应	动物模型、坐骨神经损伤、实验研究、家兔、按摩、推拿、推拿手法、类风湿关节炎、类风湿性关节炎、艾灸、血液流变学、镇痛、骨骼肌
#2绿色 #2 Green	12	灸法治疗炎性疾病	关节炎、动物、大鼠、小鼠、灸法、电针、疾病模型、穴、结肠炎、足三里、针灸疗法、间接灸
#3深蓝色 #3 Dark blue	9	穴位敷贴治疗哮喘相关呼吸道疾病	中药、动物实验、哮喘、支气管哮喘、穴位敷贴、穴位贴敷、细胞因子、行为学、豚鼠
#4浅黄色 #4 Light yellow	8	穴位注射治疗变应性鼻炎、心肌缺血，隔药灸治疗原发性痛经的疗效	临床疗效、原发性痛经、变应性鼻炎、心肌缺血、穴位注射、细胞凋亡、隔药灸、TNF-α
#5紫色 #5Purple	6	推拿治疗炎性疾病	免疫功能、推拿疗法、溃疡性结肠炎、疗效评价、肿瘤坏死因子-α、腹部推拿
#6浅蓝色 #6 Baby blue	6	机制研究	D－半乳糖、一氧化氮、丙二醛、学习记忆、超氧化物歧化酶、黄芪注射液
#7姜黄色 #7 Ginger	5	灸法治疗高脂血症	兔、环磷酰胺、隔药饼灸、高脂血症、麦粒灸

图3 推拿为关键词的标签视图（A）和推拿相关动物实验文献的关键词时间叠加可视化图（B）注：A图中，节点代表关键词，节点大小代表关键词的频次，相同颜色代表同一聚类，连线越粗，距离越近，关键词的联系越紧密。图中标注紫色类别表示腹部推拿动物实验关键词聚类；B节点代表关键词，颜色由蓝色到黄色表示时间由远及近。图中黄色凸显部分表示胰岛素抵抗机制是腹部推拿动物实验中最新研究主题。

Figure 3 Tag view with keyword massage (A) and visuali diagram of time overlay of keywords in literature of massage animal tests (B)Note： In figure A， node represents keyword， node size represents keyword frequency， the same color represents the same cluster； The thicker the line， the closer the distance， the closer the keyword connection. The purple category marked in the figure indicates the clustering of key words in animal experiments of abdominal massage. In figure B， nodes represent keywords， the color from blue to yellow indicates the time from far to near. The yellow highlighted part of the figure indicates that the mechanism of insulin resistance is the subject of recent research in animal experiments on abdominal massage.

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