实验动物与比较医学 ›› 2026, Vol. 46 ›› Issue (2): 279-287.DOI: 10.12300/j.issn.1674-5817.2025.101
收稿日期:2025-07-01
修回日期:2025-10-07
出版日期:2026-04-25
发布日期:2026-04-18
通讯作者:
蔡丽萍(1983—),女,硕士,主管技师,研究方向:实验动物应用研究、医学模拟教育。E-mail: ccg9115@126.com。ORCID: 0009-0003-5485-5506作者简介:刘意抒(1988—),女,硕士,副教授,研究方向:医学模拟教育、院校教育。E-mail: yishu1128@163.com。ORCID: 0009-0002-2989-4557
基金资助:Received:2025-07-01
Revised:2025-10-07
Published:2026-04-25
Online:2026-04-18
Contact:
CAI Liping (ORCID: 0009-0003-5485-5506), E-mail: ccg9115@126.com摘要:
当前,微创外科技术的迅猛发展对传统外科教育培训体系提出了严峻挑战,依赖实验动物的教学模式因伦理争议、成本高昂及模型局限性等问题面临转型需求。通过系统文献分析与海军军医大学第一附属医院达芬奇手术机器人培训中心的实践经验总结相结合的模式,本研究系统评估了实验动物在达芬奇机器人操作系统及腹腔镜教育培训中的多维效能。结果表明,在现有的技术条件下,实验动物凭借其真实的组织触觉反馈、动态生理响应特性及复杂术野暴露训练优势,仍是高阶手术技能培养(如血管解剖游离、器官缝合等)的核心载体,其不可替代性主要体现在术中动态生理响应模拟和紧急状况处置训练等关键教学环节。基于跨学科视角的技术评估与实践观察,笔者提出并构建了“伦理-技术协同”发展框架,并深入探讨了扩展现实(extended reality)技术的虚实融合交互机制、类器官模型的病理模拟平台构建以及数字共享平台的资源协调机制的创新价值。结合培训中心的应用案例,验证了这些技术构成“阶梯式替代”实验动物路径的潜力,并揭示了其在标准化场景复现、触觉模拟精度提升及减少实验动物使用量方面的关键突破。本研究强调,微创外科教育培训体系的变革不仅是技术创新,更是伦理观念的升级,基于伦理-技术协同的路径需重点聚焦技术整合维度构建多模态混合训练系统、资源管理维度建立生物样本协同共享网络、伦理实践维度完善动物使用必要性评估标准3大实施方向,从而为构建兼顾技术效能与伦理合规的新型培训范式体系,提供可操作的实践路径,推动外科教育向精准化、无害化转型。
中图分类号:
刘意抒,蔡丽萍. 微创外科教育培训中实验动物使用的现状分析与替代技术探索[J]. 实验动物与比较医学, 2026, 46(2): 279-287. DOI: 10.12300/j.issn.1674-5817.2025.101.
LIU Yishu,CAI Liping. Analysis of Current Practices and Exploration of Alternative Technologies in Use of Laboratory Animals for Minimally Invasive Surgery Education and Training[J]. Laboratory Animal and Comparative Medicine, 2026, 46(2): 279-287. DOI: 10.12300/j.issn.1674-5817.2025.101.
图1 达芬奇Xi手术机器人系统阶梯式培训路径
Figure 1 Da Vinci Xi Surgical System tiered training pathway
图2 腹腔镜手术培训项目
Figure 2 Laparoscopic surgical training program
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