实验动物与比较医学 ›› 2026, Vol. 46 ›› Issue (1): 127-137.DOI: 10.12300/j.issn.1674-5817.2025.072

• 实验动物福利与伦理 • 上一篇    

中国实验动物科技伦理治理体系构建与广东省实践初探

李晓琴1, 余文兰2, 段依竺1, 刘忠华2, 吴国栋1, 史文琦1, 富宏坤3()()   

  1. 1.广东省技术经济研究发展中心, 广州 510070
    2.华南农业大学, 广州 510642
    3.中国合格评定国家认可中心, 北京 100062
  • 收稿日期:2025-05-15 修回日期:2025-08-20 出版日期:2026-02-25 发布日期:2026-02-14
  • 通讯作者: 富宏坤(1989—),男,本科,高级工程师,研究方向:实验室认可。E-mail: fuhk@cnas.org.cn。ORCID: 0009-0006-8562-2942
  • 作者简介:李晓琴(1989—),女,硕士,助理研究员,研究方向:科技政策、科技管理、绩效评价。E-mail: 374513415@qq.com
    FU Hongkun (ORCID: 0009-0006-8562-2942), E-mail: fuhk@cnas.org.cn
    富宏坤,高级工程师。现任职于中国合格评定国家认可中心(CNAS)生物化学实验室认可部。长期从事食品、药品、卫生检疫、动物疾控与动植物检疫等领域的实验室认可评审相关工作;主持和参与多项科研项目,包括国家重点研发计划项目、国家市场监督管理总局科技计划项目、中国合格评定国家认可委员会科技项目等;在国内核心期刊发表论文13篇;获2020年中国合格评定国家认可中心认可科技进步奖一等奖(第四完成人)。此外,担任CNAS第五届实验室专门委员会动植物检疫与兽医专业委员会委员,全国标准样品技术委员会植物检疫标准样品专业工作组(SAC/TC118/WG18)组员。(1989—),男,本科,高级工程师,研究方向:实验室认可。E-mail: fuhk@cnas.org.cn。ORCID: 0009-0006-8562-2942
  • 基金资助:
    广东省省级科技计划项目“广东省实验动物伦理治理新路径研究”(2024A1010050007)

Construction of Laboratory Animal Science and Technology Ethics Governance System in China and Its Preliminary Practice in Guangdong Province

LI Xiaoqin1, YU Wenlan2, DUAN Yizhu1, LIU Zhonghua2, WU Guodong1, SHI Wenqi1, FU Hongkun3()()   

  1. 1.Guangdong R&D Center for Technological Economy, Guangzhou 510070, China
    2.South China Agricultural University, Guangzhou 510642, China
    3.China National Accreditation Service for Conformity Assessment, Beijing 100062, China
  • Received:2025-05-15 Revised:2025-08-20 Published:2026-02-25 Online:2026-02-14

摘要:

实验动物福利伦理是开展动物实验科学研究、从事实验动物保种饲养和管理监督等活动需要遵循的价值理念和行为规范,实验动物福利伦理保障水平与科技事业发展息息相关,这已成为国际实验动物领域的广泛共识。目前,广东省正加快推进高水平科技创新强省和粤港澳大湾区国际科技创新中心建设,应凭借较高的实验动物科技伦理治理水平推进广东省实验动物科技事业的高质量发展。本文根据中国实验动物管理法律法规和体制机制,探索优化由实验动物科技伦理治理制度保障、责任体系、伦理审查和监管机制、教育宣传等内容组成的实验动物科技伦理治理体系,基于文献研究、问卷调查和访谈调研等方法,对广东省实验动物科技伦理治理体系开展实证研究。文献及调研结果分析表明,广东省已基本建立符合目前中国实验动物科技伦理治理体系要求的实验动物管理制度、协作机制、监管机制和教育培训体系,但仍然存在实验动物科技伦理监管机制不健全、审查机构运行机制不够完善、实验动物单位对动物实验伦理审查不够重视、伦理审查标准不统一,以及伦理审查人员缺乏伦理专业的教育和培训等问题,由此提出健全实验动物科技伦理审查体系、加强监督检查、进一步压实主体责任、研制审查规范和加强分级分类教育培训等优化举措,为推动广东省实验动物科技伦理的常态化长效化治理提供理论依据。

关键词: 实验动物科技伦理治理体系, 审查和监管机制, 实验动物福利伦理委员会, 教育培训, 广东省

Abstract:

The welfare and ethics of laboratory animals are the ethical principles and behavioral norms that need to be followed in conducting animal-based scientific research, breeding and managing laboratory animals, and supervising and regulating such activities. The level of protection of laboratory animal welfare and ethics is closely related to the development of science and technology, which has become a widely recognized international consensus. At present, Guangdong Province is accelerating the construction of a high-level science and technology innovation province and the Guangdong-Hong Kong-Macao Greater Bay Area International Science and Technology Innovation Center. Guangdong Province should rely on its advanced governance capacity in the field of laboratory animal science and technology ethics to promote the high-quality development of its laboratory animal science and technology sector. Based on the management laws, regulations, and institutional mechanisms of laboratory animals in China, this paper explores the optimization of the laboratory animal science and technology ethics governance system, which includes the institutional guarantees, responsibility systems, ethical review and supervision mechanisms, and education and outreach. Through methods such as literature research, questionnaire surveys, and interview investigations, an empirical study of the laboratory animal science and technology ethics governance system in Guangdong Province has been conducted. Analysis of literature and research results shows that Guangdong Province has basically established a laboratory animal management system, collaboration mechanism, supervision mechanism, and education and training system that meet the current requirements of the laboratory animal science and technology ethics governance system in China. However, there are still problems such as an incomplete laboratory animal science and technology ethics supervision mechanism, an underdeveloped operation mechanism of review institutions, insufficient attention paid by laboratory animal units to the ethical review of animal experiments, inconsistent ethical review standards, and a lack of professional ethical education and training for ethics review personnel. Therefore, optimization measures such as improving the laboratory animal science and technology ethics review system, strengthening supervision and inspection, further strengthening the accountability of responsible entities, formulating review norms, and enhancing hierarchical and classified education and training are proposed, to provide a theoretical basis for promoting the normalized and long-term governance of laboratory animal science and technology ethics in Guangdong Province.

Key words: Laboratory animal science and technology ethics governance system, Review and supervision mechanisms, Laboratory animal welfare and ethics committee, Education and training, Guangdong Province

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