›› 2005, Vol. 25 ›› Issue (3): 182-185.

• 论文 • 上一篇    下一篇

微卫星标记技术及其应用

  

  1. 温州医学院实验动物中心,温州 325027
  • 收稿日期:2004-11-26 出版日期:2005-01-25 发布日期:2013-03-19

Microsatellite Technology and their Applicationin

  1. Laboratory Animal Center, Wenzhou Medical College, Wenzhou 3250027, China
  • Received:2004-11-26 Online:2005-01-25 Published:2013-03-19

摘要: 微卫星标记具有数量多、在基因组中分布广、多态性丰富、呈孟德尔共显性遗性、检测快速方便等特点。本文简述了微卫星技术基本原理、优点和检测方法以及在实验动物科技等领域中的应用,例如遗传连锁图谱、分子标记辅助育种、遗传多样性分析、遗传质量检测等。

关键词: 微卫星, 分子标记, 实验动物, 应用

Abstract: Microsatellite marker has many advantages such as a great quantity, extensive dispersion around the genome, high polyomorphism, Mendelian codominant inheritance, rapid and convenient detection. In this paper,it were briefly introduced principle and structure, the application of microsatellite technique was reviewed in the study of animal, for instance, construction of genetic linkage map, molecular marker assisted breeding, evaluation of genetic diversity, genetic monitoring and so on were summarized.

Key words: Microsatellite, Molecular markers, Laboratory animal, Application