›› 2010, Vol. 30 ›› Issue (1): 44-47.

所属专题: 实验动物资源开发与利用

• 论文 • 上一篇    下一篇

WHBE兔的血液学指标测定与比较

  

  1. 浙江中医药大学动物实验研究中心,比较医学研究中心,杭州 310053
  • 收稿日期:2009-03-17 出版日期:2010-01-31 发布日期:2010-01-31
  • 基金资助:
    1.浙江省公共科技基础平台项目(Dwpt-bz-12,2007F8003),2.浙江省卫生高层次创新人才培养工程项目。

Determination and Comparison of Hematological Indices in WHBE Rabbits

  1. Zhejiang Chinese Medical University Laboratory Animal Research Center; Hangzhou 310053,China
  • Received:2009-03-17 Online:2010-01-31 Published:2010-01-31

摘要: 目的 测定和比较分析WHBE兔、日本大耳白兔、新西兰白兔的血液学指标,揭示WHBE兔的血液学特性.方法 选择WHBE兔、日本大耳白兔、新西兰白兔各40只,雌雄各半,耳动脉采血,应用Bayer ADVIA 120五分类血球分析仪测定红细胞、白细胞、血小板等血液细胞参数.结果 ①性别因素对WHBE兔的%NEUT、%LYMP、MCH、MCHC、RDW等有显著差异(P<0.05,P</i><0.01),其它指标雌雄性别间均无显著差异(P>0.05);②WHBE兔的白细胞参数和红细胞参数与日本大耳白兔和新西兰白兔存在着显著差异,如白细胞数目明显低于日本大耳白兔(P</i><0.01),淋巴细胞和血红蛋白含量均明显高于日本大耳白兔和新西兰白兔(P</i><0.01).结论 WHBE兔有其自身的特性,也有其兔种群的共性,WHBE兔的血液学生理指标与人类较为接近.

关键词: WHBE兔, 日本大耳白兔, 新西兰白兔, 血液学

Abstract: Objective To determine and comparative analysis of hematological parameters in WHBE rabbits, Japanese White rabbits and New Zealand White rabbits,and further reveal on hematological characteristics of WHBE rabbits. Methods Fourty in each of WHBE rabbits, Japanese White rabbits and New Zealand White rabbits,half male and female, the anticoagulant blood was sampled from the central artery of ear, and then hematological parameters indexes were determined by Bayer AD VIA 120 automatic blood analyzer. Results (1) Gender factor has significant influences on neutrophil, lymphocyte, MCH, MCHC and RDW m WHBE rabbits (P<0.05, P<0.01);(2) Leukocytes amounts was lower in WHBE rabbits than that of Japanese White rabbits (P<0.01),lymphocyte and hemoglobin were higher in WHBE rabbits than those of Japanese White rabbits and New Zealand White rabbits (P<0.01).Conclusion WHBE rabbit has its own special characteristics, also has its population characteristics in common, and the hematological parameters in WHBE rabbits were similar to those of human being.

Key words: WHBE rabbit, Japanese White rabbit, New Zealand White rabbit, Hematological parameter