实验动物与比较医学 ›› 2012, Vol. 32 ›› Issue (5): 446-448.DOI: 10.3969/j.issn.1674-5817.2012.05.016

• 论著 • 上一篇    下一篇

食蟹猴水痘带状疱疹病毒相关抗体研究初探

桑传兰1, 多海刚2, 张永斌1, 陈嘉1, 饶军华2   

  1. 1.广州中医药大学实验动物中心, 广州 510405;
    2.广东蓝岛生物技术有限公司, 广州 510555
  • 收稿日期:2012-03-07 出版日期:2012-10-25 发布日期:2012-10-25
  • 作者简介:桑传兰(1970-),女,硕士,助理研究员,主要从事实验动物学研究,E-mail:1661767317@qq.com

Preliminary Probe of Detection of Simian Varicella Virus Antibodies in Cynomolgus Monkey

SANG Chuan-lan1, DUO Hai-gang2, ZHANG Yong-Bin1, CHEN Jia, Rao Jun-hua2   

  1. 1. Laboratory Anima Center Guangzhou University of Traditional Chinese Medicine, 510405, China;
    2. Guangdong Landau Biotechnology Co.,Ltd,Guangzhou,510555, China
  • Received:2012-03-07 Online:2012-10-25 Published:2012-10-25

摘要: 目的 初步了解食蟹猴猴水痘带状疱疹病毒感染情况。方法 用水痘带状疱疹病毒IgG ELISA试剂盒对经B病毒抗体检测为阴性的中国3个猴场的3岁左右食蟹猴,进行猴水痘带状疱疹病毒(SVV)抗体检测。结果 3个猴场SVV抗体阳性率分别是14.55%,30.95%,27.66%。在血清学测试期间,所有血清阳性的猴没有出现皮疹。结论 猴感染水痘带状疱疹病毒后, 会潜伏在神经节,激活后产生带状疱疹症状,这是一种潜在风险,应引起重视。

关键词: 食蟹猴, 水痘带状疱疹病毒, 抗体, 检测

Abstract: Objective To find out epizootic of simian varicella virus occurring in cynomolgus monkey. Methods Using varicella-zoster virus IgG ELISA kit to detect cynomolgus monkey sera Ł¬from three facilities,which is B virus antibodies negative. Result The positive rate of simian varicella virus antibodies were 14.55%,30.95%,27.66% in three guangxi breeding facilities, respectively. During the serological tests, all the positive cynomolgus monkeys didn’t develop a rash. Conclusion After infection with Simian varicella virus,the virus becomes latent in ganglia, and can reactivate to produce zoster. This potential risk shoud be paid more attention.

Key words: Cynomolgus monkey, Simian varicella virus, Antibodies

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