›› 2010, Vol. 30 ›› Issue (1): 73-76.

• 论文 • 上一篇    

镉对斑马鱼胚胎发育毒性的研究进展

  

  1. 1.上海市计划生育科学研究所,上海 200032;2.复旦大学公共卫生学院,上海 200032
  • 收稿日期:2009-09-18 出版日期:2010-01-31 发布日期:2010-01-31
  • 基金资助:
    上海市公共卫生重点学科建议项目(08GWZX0301)

Advances on Developmental Toxicity of Cadmium in Zebrafish Embryos

  1. 1.Public Health School of Fudan University, Shanghai 200032, China;2.Shanghai Institute of Planned Parenthood Research Shanghai 200032,China
  • Received:2009-09-18 Online:2010-01-31 Published:2010-01-31

摘要: 镉是一种广泛存在于生产和生活环境中的非必需重金属元素.镉染毒动物可出现多器官损害作用.本文综述了镉对斑马鱼胚胎体轴和肌节、血管、脑部及神经系统的发育的影响及可能机制,为深入研究镉对其他高等脊椎动物生长发育的影响提供了参考依据.

关键词: 斑马鱼, 镉, 发育毒性, 机制

Abstract: Cadmium is a widespread non-essential heavy metal in occupational and living environment.It is toxic to multiple organs in animals. This review is given on advanced data on potential developmental toxicity as well as the mechanisms of cadmium in zebrafish embryos which provides a reference for further studies on toxicological effects of cadmium in the development of other vertebrates.

Key words: Zebrafish, Cadmium, Developmental toxicity, Mechanism