关键词: 英国短毛猫, 实验动物, 血液生理, 血液生化, 参考值

Abstract: Objective To study sexual and age differences of hematological and blood biochemical values in laboratory British-shorthair cats and to provide the basis for the cat related research. Methods Hematological parameters and blood biochemical indices of laboratory British-shorthair cats at 5 month old and 11 month old were measured, and the results were compared according to age and gender. Results There were age-related difference in 2 hematological indicators of female cats[hemoglobin(HGB), hematocrit(HCT)and in 5 indicators of male cats[HCT, mean corpuscular volume(MCV), erythrocyte(RBC), HGB, and mean corpsular hemoglobin(MCH)]. Sexual difference were observed in 2 hematological data [leukocyte(WBC), lymphocyte(LYMPH)from 5 month old cats and in 3 hematological data(RBC, HGB, LYMPH%) from 11 month old cats. Among the blood biochemical values, age-related difference exist in 4 parameters of female cats[alkaline phosphatase (ALKP), phosphorus(PHOS), cholesterol (CHOL) and creatinine(CREA)]as well as in 3 parameters of male cats(ALKP, PHOS, CREA), gender effect were also observed on CHOL of female cats and on 3 variables of male cats[albumin(ALB), CREA and alanine aminotransferase(ALT)]. Conclusion There are gender difference in some hematological and biochemical values of laboratory British-shorthair cat both in 5 month old and in 11 month old, as well as age-related difference between 5 month old cats and 11 month old cats. Our finding indicate that effects of gender and age should be taken into consideration in establishing hematological and biochemical reference intervals of laboratory British-shorthair cat.

Key words: British-shorthair cat, Laboratory animal, Hematology, Biochemistry, Reference