›› 1999, Vol. 19 ›› Issue (4): 210-212.

• 论文 • 上一篇    下一篇

实验性急性肾衰竭犬的肾核素动态显像观察

  

  1. 第一军医大学实验动物学教研室,广州 510515
  • 收稿日期:1999-01-14 出版日期:1999-01-25 发布日期:2013-03-19

Radionuclide Dynamic Imaging of Acute Renal Failure in Dogs

  • Received:1999-01-14 Online:1999-01-25 Published:2013-03-19

摘要: 用核素显像法对甘油所致急性肾衰犬(n=15)的肾进行动态显像观察。结果,经过27.3±1.7s肾完全显影,经264.1±18.4s肾内放射性元素达到峰值,显影过程明显慢于注射甘油前(P<0.01)。并从肾脏不同时期的血流变化,计算出肾小球滤过率为23.5±11.4ml/min,明显低于注射甘油前(110.0±14.6ml/min,P<0.01)。

关键词: 急性肾功能衰竭, 核素显像, 肾小球滤过率,

Abstract: The radionuclide dynamic imaging method was applied to study acute renal failure induced by intramuscular injection with glyceryl alcohol in 15 dogs. The results showed that 0.5~6 hours after the injection the time taken for completely imaging of renes and the time for reaching peak level of radionuclide in ren were longer than those before the injec-tion(27.3±1.7 seconds vs 17.4± 1.8 seconds,P<0.01,264.1±18.4 seconds vs 152.4±18.1 seconds ,P<0.01,respectively), while the glomerular filtration rate(GFR) was less than that before the injection (23.5±11.4 ml/min vs 110.0±14.6 ml/min).

Key words: "Acute renal failure, Radionuclide imaging, Dog, Glyceryl alcohol "