实验动物与比较医学 ›› 2016, Vol. 36 ›› Issue (6): 441-446.DOI: 10.3969/j.issn.1674-5817.2016.06.008

所属专题: 实验动物资源开发与利用

• 论著 • 上一篇    下一篇

四个品种小型猪血液学指标测定及比较

杨李厂1, 周文兵1, 丁隽1, 周新初2, 张建平3, 谢东1, 杨伟敏1   

  1. 1.上海睿智化学研究有限公司, 上海 201203;
    2.上海交通大学农业与生物学院, 上海 200240;
    3.上海甲干生物技术有限公司,上海 201112
  • 收稿日期:2016-06-21 出版日期:2016-12-25 发布日期:2016-12-25
  • 作者简介:杨李厂(1981- ), 男, 硕士, 研究方向: 动物生理/生化。 E-mail: lchyang@chempartner.cn
  • 基金资助:
    上海市实验动物创新行动计划项目 (13140900200)

Investigation on Biological Characteristics of Blood for Four Breeds of Minipigs

YANG Li-chang1, ZHOU Wen-bing1, DING Jun1, ZHOU Xin-chu2, ZHANG Jian-ping3, XIE Dong1, YANG Wei-min1   

  1. 1. Shanghai Chempartner Co. Ltd, Shanghai 201203, China;
    2. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China;
    3. Shanghai Jiagan Bio-tech Co. Ltd, Shanghai 201112, China
  • Received:2016-06-21 Online:2016-12-25 Published:2016-12-25

摘要: 目的 分析比较四个品种小型猪的血液学生物学特性。方法 分别选取上海地区饲养的巴马小型猪、贵州小型猪和版纳小型猪及陆川小型猪,每个品种雌雄各20头,3~6月龄,测量其 血液生理、血清生化与血凝指标,然后进行单因素方差分析,并进行数据比较。结果 四个品种的小型猪血液生理14个指标差异有统计学意义( P<0.05),血清生化12个指标组间差异有统计学意义( P<0.05),血凝4个指标差异都有统计学意义(P <0.05)。分别对各品种群体数据进行比较分析,巴马小型猪群体雌雄间血液常规、血清生化和血凝指标差异显著( P<0.05)的指标分别有6项、4项和3项,而贵州小型猪、版纳小型猪和陆川小型猪雌雄间差异指标较少或差异不显著。四品种小型猪相同性别间比较,也有较多指标差异显著。结论 测定和比较的巴马小型猪、贵州小型猪、版纳小型猪和陆川小型猪在血液学、血清生化和血凝等方面数据,为应用和选择小型猪开展相关生物医学和药物研究提供了基础数据。

关键词: 巴马小型猪, 贵州小型猪, 版纳小型猪, 陆川小型猪, 血液生理, 血清生化, 血凝

Abstract: Objective To analyze and compare of the biological characteristics of the blood of four breeds of minipigs. Method The four breeds of minipigs including Bama minipigs, Guizhou minipigs, Banna minipigs and Luchuan minipigs at the age of 3 to 6 months reared in Shanghai area were selected to determine the hematology, serum biochemistry and blood coagulation values with 40 (half males and half females) in each breed. All data were analyzed by one-way ANOVA method and then compared. Result Among the four breeds of minipigs, 14 parameters of hematology, 12 parameters of serum biochemistry and 4 parameters of blood coagulation were significant different (P<0.05). Compared the results between males and females, 6 hematologic parameters, 4 serum biochemistry parameters and 3 blood coagulation parameters in Bama minipig were significantly different (P<0.05), a few parameters or no parameters of blood in Guizhou minipigs, Banna minipigs and Luchuan minipigs were significant different. There are many parameters existing significant different between same gender among four minipigs breeds. Conclusion The parameters of hematology, serum biochemistry and blood coagulation of Bama minipigs, Guizhou minipigs, Banna minipigs and Luchuan minipigs provide the abundant biological data support when applying and selecting minipig for medical science model research and pharmaceutical research.

Key words: Bama minipig, Guizhou minipig, Banna minipig, Luchuan minipig, Hematology, Serum biochemistry, Blood coagulation

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