实验动物与比较医学 ›› 2019, Vol. 39 ›› Issue (1): 72-76.DOI: 10.3969/j.issn.1674-5817.2019.01.014

• 综述 • 上一篇    下一篇

子宫内膜异位症大鼠模型研究进展

纪莲1, 马铁2, 刘冬妍1   

  1. 中国医科大学附属盛京医院 1.实验研究中心, 2.病理科, 沈阳 110004
  • 收稿日期:2018-06-15 出版日期:2019-02-25 发布日期:2021-01-29
  • 作者简介:纪莲(1982-),女,助理实验师。

Research Advances in Rat Model of Endometriosis

JI Lian1, MA Tie2, LIU Dong-yan1   

  1. 1. Department of Medical Research Center; 2. Department of Pathology,Shengjing Hospital, China Medical University, Shenyang 110004, China
  • Received:2018-06-15 Online:2019-02-25 Published:2021-01-29

摘要: 为临床深入研究子宫内膜异位症(EMs)的病因、发病机制、治疗药物和预防对策提供合理的大鼠模型。本文对EMs大鼠模型的发病机制、建模方法、优化措施、评价标准以及模型应用等进行综合阐述和比较,研究者可根据实验需要选择合适的建模方法,使其更加贴合实验及临床研究的需要。

关键词: 子宫内膜异位症(EMs), 大鼠, 建模方法

Abstract: In order to establish reliable rat model to study the etiology, pathogenesis and treatment of endometriosis, this article reviewed the literature on the rat model of endometriosis, including the pathogenesis, modeling method, the refinement, evaluation criterion and the application of rat endometriosis model. This review may offer an important reference for choosing animal models to study endometriosis in the future.

Key words: Endometriosis, Rat, Model

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