实验动物与比较医学 ›› 2024, Vol. 44 ›› Issue (6): 645-653.DOI: 10.12300/j.issn.1674-5817.2024.113

• 各地实验动物科学发展 • 上一篇    下一篇

风雨五十载,奋斗半世纪——记苏州市实验动物产业发展五十年

赵丽娟(), 肖春兰, 盛雅洁, 鲁希, 周正宇()()   

  1. 苏州大学苏州医学院实验动物中心, 苏州 215123
  • 收稿日期:2024-08-02 修回日期:2024-10-12 出版日期:2025-01-04 发布日期:2024-12-25
  • 通讯作者: 周正宇(1973—),男,博士,教授,研究方向:动物模型和比较医学。E-mail: zacharyzhou@suda.edu.cn。ORCID: https://orcid.org/0000-0001-5712-9495
  • 作者简介:赵丽娟(1988—),女,硕士研究生,助理实验师。研究方向:实验动物学。E-mail: ljzhao@suda.edu.cn
    周正宇,博士研究生,教授,博士生导师。从事维生素D与糖尿病、动物模型与比较医学研究,担任苏州大学苏州医学院实验动物中心主任。兼任苏州市实验动物协会理事长,中国实验动物学会实验动物机构认证工作委员会委员、实验动物标准化专业委员会委员、实验动物饲料与营养专业委员会委员,江苏省动管办专家组成员、专业标准化技术委员会委员,江苏省动物学会理事,江苏省实验动物协会副理事长,《中国比较医学杂志》和《实验动物与比较医学》编委。同时承担苏州医学院研究生专业基础课程《实验动物学》教学工作。曾获得首届中国实验动物学会、中国药理学会、中国毒理学会优秀论文奖,江苏省实验动物管理先进个人,苏州市科技进步二等奖、三等奖,苏州市自然科学优秀论文二等奖。 (ORCID: https://orcid.org/0000-0001-5712-9495), E-mail: zacharyzhou@suda.edu.cn

Challenges and Development in Suzhou Laboratory Animal Industry Over the Past Five Decades

ZHAO Lijuan(), XIAO Chunlan, SHENG Yajie, LU Xi, ZHOU Zhengyu()()   

  1. Laboratory Animal Center of Suzhou Medical College, Soochow University, Suzhou 215123, China
  • Received:2024-08-02 Revised:2024-10-12 Published:2024-12-25 Online:2025-01-04
  • Contact: ZHOU Zhengyu (ORCID: 0000-0001-5712-9495), E-mail: zacharyzhou@suda.edu.cn

摘要:

从20世纪70年代开始,苏州市实验动物产业经历了起步、兴起、壮大、转型、规模化五个阶段。始于实验动物的笼器具,从最初的引进模仿到自主创新,规模从零星工厂走向集聚化、集团化的企业,产业逐渐兴起壮大,并打开了我国笼器具出口的大门。21世纪产业升级转型,净化工程和配套产品开始发展,行业组织诞生。随着我国现代化水平的提升,自动化、智能化生产的潮流带来了企业的科技创新和实验动物行业各项外包服务的涌现,产业链的发展走向规模化。经过了近半个世纪的成长,苏州市实验动物产业已形成了包括实验动物、笼器具、饲料垫料生产,实验动物设施设计与施工,实验动物与环境质量检测,动物实验等服务在内的完整产业链。实验动物饲养设备作为苏州市实验动物产业核心已达到发达国家水平,产业规模和影响力在国内同类行业中独树一帜。与此同时,21世纪以来,生物医药成为苏州大力发展的“一号产业”。在政府的支持、地方经济的引领、高校和科研院所的助力下,动物实验服务外包行业开始集聚苏州,CRO机构的不断涌入促使大规模实验动物设施纷纷新建,重点研发项目先后立项、研发能力大幅提升。苏州市实验动物产业与“一号产业”同频共振快速扩张,走出了一条实验动物的“苏州之路”。在将近五十载的岁月中,苏州市实验动物产业支撑着苏州乃至我国生物医药产业的快速发展。

关键词: 苏州, 实验动物, 笼器具, 独立通风笼盒

Abstract:

Since the 1970s, the laboratory animal industry in Suzhou has gone through five stages: its inception, emergence, growth, transformation, and scaling up. It began with the manufacturing of caging equipment for laboratory animals, initially by imitation and later through independent innovation. The industry evolved from sporadic factories to clustered enterprises, gradually growing and opening up the export market for caging equipment. In the 21st century, with industrial upgrading and transformation, purification systems and related products began to develop, and industry organizations emerged. As China has modernized, the rise of automation and intelligent production has led to technological innovation in enterprises and the emergence of various outsourcing services in the laboratory animal industry, driving the large-scale development of the industrial chain. After nearly half a century of growth, the laboratory animal industry in Suzhou has formed a complete industrial chain, including the production of laboratory animals, caging equipment, feed and bedding materials, design and construction of laboratory animal facilities, quality testing of laboratory animals and environments, and animal experimentation services. Laboratory animal breeding equipment, the core of the industry, has reached the level of developed countries, and the industry's scale and influence are unmatched in China. Since the 21st century, biopharmaceuticals have become the "No.1 industry" in the development of Suzhou. With government support, the guidance of the local economy, and the assistance from universities and research institutes, the animal experiment outsourcing industry has begun to cluster in Suzhou. The continuous influx of CROs has driven the construction of large-scale laboratory animal facilities, and key research projects have been initiated, significantly enhancing the industry's R&D capabilities. The Suzhou laboratory animal industry has quickly expanded alongside the "No. 1 industry," creating a unique "Suzhou Path" for laboratory animals. Over nearly fifty years, the laboratory animal industry in Suzhou has been essential to the rapid development of the biopharmaceutical industry in Suzhou and China.

Key words: Suzhou, Laboratory animal, Caging equipment, Individually ventilated cages

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