实验动物质量控制中泰泽病原体的研究进展

doi:10.12300/j.issn.1674-5817.2021.166

摘要/Abstract

摘要：

泰泽病原体（Tyzzer’s organism）是一种能引起实验动物肝肠坏死和腹泻的毛发状芽孢杆菌（Clostridium piliforme，旧称Bacillus piliformis）。该病原体引起的泰泽病是一种急性疾病，其发病迅速、致死率高、临床症状不明显，往往难以进行早期诊断和治疗，一旦爆发，将会造成严重的经济损失和实验室安全问题。本文从泰泽病原体的生物学特性、流行病学与疾病特征、检测方法、研究进展及防治多个方面进行综述。

关键词: 泰泽病原体, 泰泽氏病, 研究进展, 防治

Abstract:

Tyzzer's organism is a kind of Clostridium piliforme, formerly Bacillus piliformis, which can cause hepatointestinal necrosis and diarrhea in animals. Tyzzer's disease caused by this pathogen is an acute disease with rapid onset, high mortality and no obvious clinical symptoms, so it is difficult to make early diagnosis and treatment. Once the outbreak, it will cause irreparable economic losses and laboratory safety problems. This article reviewed the biological characteristics, epidemiological and disease characteristics, detection methods, research progress of Tyzzer's organism, as well as the prevention and treatment of Tyzzer's organism.

Key words: Tyzzer organism, Tyzzer disease, Research progress, Prevention and treatment

中图分类号:

Q95-33

陶俊豪, 鄢慧琼, 谢珲, 应华忠, 戴方伟. 实验动物质量控制中泰泽病原体的研究进展[J]. 实验动物与比较医学, 2022, 42(4): 358-363.

Junhao TAO, Huiqiong YAN, Hui XIE, Huazhong YING, Fangwei DAI. Research Progress of Tyzzer’s Organism in Quality Control of Laboratory Animals[J]. Laboratory Animal and Comparative Medicine, 2022, 42(4): 358-363.

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