实验动物与比较医学 ›› 2021, Vol. 41 ›› Issue (3): 195-206.DOI: 10.12300/j.issn.1674-5817.2021.086

所属专题: 专家论坛 实验动物伦理与福利专辑

• 创刊40周年专题:标准与指南 • 上一篇    下一篇

2020版美国兽医协会动物安乐死指南解析

卢今1, 张颖2, 潘学营3, 王剑1, 严国锋1, 周晶1, 朱莲1, 陈学进1,4, 李垚1, 庞万勇5   

  1. 1.上海交通大学医学院实验动物科学部,上海 200025;
    2.北京海关,北京 100026;
    3.上海益诺思生物技术股份有限公司,上海 201203;
    4.香港中文大学(深圳)生命与健康学院,深圳 518172;
    5.赛诺菲公司全球研发中心转化体内模型研究平台,北京 100022
  • 收稿日期:2021-04-25 修回日期:2021-05-31 出版日期:2021-06-25 发布日期:2021-07-05
  • 作者简介:卢 今(1990—), 女, 兽医学硕士, 研究方向: 实验动物医学。E-mail: ashleelu@shsmu.edu.cn

A Brief Interpretation of AVMA Guidelines on Euthanasia of Animals: 2020 Edition

LU Jin1, ZHANG Ying2, PAN Xueying3, WANG Jian1, YAN Guofeng1, ZHOU Jing1, ZHU Lian1, CHEN Xuejin1,4, LI Yao1, PANG Wanyong5   

  1. 1. Department of Laboratory Animal Science, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China;
    2. Beijing Customs District P.R.China, Beijing 100026, China;
    3. Shanghai Innostar Biotechnology Co., Ltd., Shanghai 201203, China;
    4. School of Life and Health Sciences, Chinese University of Hong Kong (Shenzhen), Shenzhen 518172, China;
    5. Translational In Vivo Model Research Platform,Sanofi G&D, Beijing 100022, China
  • Received:2021-04-25 Revised:2021-05-31 Online:2021-06-25 Published:2021-07-05

摘要: 巴比妥酸盐及其衍生物的过量注射是绝大多数动物种类首选的安乐死方法,然而在此类药物不能或很难获得时,兽医可参考美国兽医协会现行版《动物安乐死指南》(AVMA Guidelines for the Euthanasia of Animals)(简称《指南》)选用其他合适的安乐死方法。2020版《指南》根据最新的研究文献,对现有的安乐死方法、技术和药物进行补充及修改。本文总结了2020版《指南》的更新内容,并在此基础上归纳列举了适用于常见实验动物种类的首选安乐死方法、条件性接受安乐死方法和不可接受的安乐死方法,另外简述了实施动物安乐死的基本原则和注意事项。

关键词: 实验动物, 安乐死, 可接受性安乐死方法, 条件性接受安乐死方法, 注意事项

Abstract: Overdose of injectable barbiturates or barbituric acid derivatives is the most preferred euthanasia method for the majority of animal species. However, these controlled drugs have limited access, and in this case or in any other scientific concerns, veterinarians may choose alternative, conditional acceptable methods as recommended by American Veterinary Medical Association (AVMA) Guidelines for the Euthanasia of Animals. In the newest 2020 Edition, existing euthanasia methods, techniques and agents of euthanasia are updated according to recently released articles. This article summarized the updated content of the new version of the AVMA Guidelines and on this basis, enumerated the most preferred methods of euthanasia, methods acceptable with conditions and unacceptable methods to euthanize different animal species. In addition, principles and precautions related to animal euthanasia were also briefly described.

Key words: Laboratory animal, Euthanasia, Acceptable euthanasia methods, Euthanasia methods acceptable with conditions, Precautions

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