关键词: 产后压力性尿失禁, 动物模型, 尿动力学, 喷嚏试验

Abstract: Objective To observe the injury of pelvic muscle and change of pelvic function after the establishment of postpartum urinary incontinence (PPUI) animal model. Methods To establish PPUI animal model, a hyponome was placed in the rat vagina for a long time to imitate the way in which birth trauma destructs the rat pelvic floor and then sneezing experiment, urodynamic test (largest bladder capacity, leak point pressure), and the histological identification was made for observing the function of pelvic floor muscle contraction strength respectively after 1 day, 7 days 14 days, 28 days, 56 days. Results Urodynamics (largest bladder capacity, leak point pressure) and pelvic floor muscle contrac-tion strength changed in the rats of the test team. Conclusion Placing a hyponome in the rat vagina for a long time to imitate the way in which birth trauma destructs the rat pelvic floor can establish a PPUI animal model like the postpartum urinary incontinence Zs symptom in human.

Key words: Postpartum urinary incontinence, Animal model, Urodynamics, Sneeze test