Laboratory Animal and Comparative Medicine ›› 2012, Vol. 32 ›› Issue (6): 489-492.DOI: 10.3969/j.issn.1674-5817.2012.06.007

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Establishing a New bone- tendon Junction Injure Model in Rat Facilitating MRI Detection

LIANG Pei-hong, LI Ai-guo, HE Ming-chong, ZHONG Ming-zhi, CHEN Shong, LIANG Zhi-ping, YANG Xiao-hong, WANG Wen, CHEN Hong-hui   

  1. The Fourth Affiliated Hospital of Jinan University, Institute of Traum atology, Guangzhou 510220, China
  • Received:2012-06-06 Online:2012-12-25 Published:2012-12-25

Abstract: Objective To establish a new bone-tendon junction injury animal models for better observation with MRI. Methods The patella of 12 mature New Zealand white rabbits were partially resected and then the tendon were sutured to bone.General examination and MRI were done after 2, 4, 8 and 12 weeks. Results The general examination and MRI results showed the healing process of bone-tendon junction dynamically in 2, 4, 8, 12 weeks after operation. The process was featured as cancellous bone regeneration and bone- tendon healing contact fibrocartilage zone regeneration, which was restored gradually as time pasted. Conclusions The modified animal models do not affect bone-tendon junction healing and is better for MRI observation correctly.

Key words: Bone-tendon junction, Animal model, MRI

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