Depression in Rat Model Sucrose Preference Test Data Analysis of Aggregation

doi:10.3969/j.issn.1674-5817.2012.03.002

Abstract

Abstract: Objective To explore the rat model depression sucrose preference test (Sucrose preference test, SPT) in sucrose preference value SP (Sucrose preference) the best aggregation. Methods Chronic mild stress (CMS) rat model of depression was replicated. In the four weeks of modeling process, gathering a sucrose preference test data for every other week, and the sucrose preference test data using twi-two aggregation analysis approach. Aggregation of different means than the preparation of model reliability and correlation effects. Result ① Kappa TM showed only way to get a higher aggregate reliability (Kappa = 0.611), ② ICC results showed that the aggregation of TM's credibility highest (ICC = 0.910)). Conclusion The appropriate data aggregation can significantly improve depression in rats with sucrose preference test data credibility and stability.

Key words: Depressive mood, Sucrose preference test, Animal model, Data aggregation, Correlation

CLC Number:

Q95-33

HOU Jin-liang, WEI Sheng, DU Xi-yang, ZHANG Hui-yun. Depression in Rat Model Sucrose Preference Test Data Analysis of Aggregation[J]. Laboratory Animal and Comparative Medicine, 2012, 32(3): 182-185.

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