Establishment of Induced Animal Model with Thymic Lymphoma

doi:10.3969/j.issn.1674-5817.2011.06.019

Abstract

Abstract: Thymoma is the most common mediastinal tumor, its etiology and pathogenesis is unclear. It is an invasive important means to establish suitable animal model for studing its etiology, pathogenesis and treatment. In this paper, we review some thymoma tumor model induced by carcinogens such as physical, chemical and biological factors . At the same time their trigger mechanism and influenced factors were also reviewed Then we simply introduce the advantages of the induced thymoma model.

Key words: Thymoma, Chemical factors, EBV, Ionizing radiation, Animal models

CLC Number:

R73
Q95-33

WANG Hong-yan, SONG Xiang-fu, CHEN Yu-bing, GONG Shou-liang. Establishment of Induced Animal Model with Thymic Lymphoma[J]. Laboratory Animal and Comparative Medicine, 2011, 31(6): 478-482.

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