doi:10.12300/j.issn.1674-5817.2025.025

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Q95-33

References 21

1	孙强. 为什么要开展动物实验[J]. 实验动物与比较医学, 2024, 44(1): 121-126. DOI:10.12300/j.issn.1674-5817.2023.177 .
2	孙强. 如果动物实验不严谨[J]. 实验动物与比较医学, 2024, 44(2): 234-237. DOI:10.12300/j.issn.1674-5817.2024.039 .
3	CLAYTON J A, COLLINS F S. Policy: NIH to balance sex in cell and animal studies[J]. Nature, 2014, 509(7500):282-283. DOI:10.1038/509282a .
4	BEERY A K, ZUCKER I. Sex bias in neuroscience and biomedical research[J]. Neurosci Biobehav Rev, 2011, 35(3):565-572. DOI:10.1016/j.neubiorev.2010.07.002 .
5	WOITOWICH N C, BEERY A, WOODRUFF T. A 10-year follow-up study of sex inclusion in the biological sciences[J]. eLife, 2020, 9: e56344. DOI:10.7554/eLife.56344 .
6	PRENDERGAST B J, ONISHI K G, ZUCKER I. Female mice liberated for inclusion in neuroscience and biomedical research[J]. Neurosci Biobehav Rev, 2014, 40:1-5. DOI:10.1016/j.neubiorev.2014.01.001 .
7	BEERY A K. Inclusion of females does not increase variability in rodent research studies[J]. Curr Opin Behav Sci, 2018, 23:143-149. DOI:10.1016/j.cobeha.2018.06.016 .
8	COLLINS F S, TABAK L A. Policy: NIH plans to enhance reproducibility[J]. Nature, 2014, 505(7485):612-613. DOI:10.1038/505612a .
9	HEALTH-CANADA. Health portfolio sex - and gender-based analysis plus policy: advancing equity, diversity and inclusion [EB/OL]. (2023-01-27)[2025-02-25]. https://www.canada.ca/en/health-canada/corporate/transparency/heath-portfolio-sex-gender-based-analysis-policy.html.
10	National Institutes of Health. Consideration of sex as a biological variable in NIH-funded research[EB/OL]. (2015-06-19)[2025-02-25]. https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-102.html.
11	Cleveland Clinic. Early warning signs of a heart attack[EB/OL]. (2024-09-16)[2025-02-25]. https://health.clevelandclinic.org/early-signs-of-a-heart-attack.
12	SKELLY D A, SQUIERS G T, MCLELLAN M A, et al. Single-cell transcriptional profiling reveals cellular diversity and intercommunication in the mouse heart[J]. Cell Rep, 2018, 22(3):600-610. DOI:10.1016/j.celrep.2017.12.072 .
13	KLEIN S L, FLANAGAN K L. Sex differences in immune responses[J]. Nat Rev Immunol, 2016, 16(10):626-638. DOI:10.1038/nri.2016.90 .
14	FAIRWEATHER D, ROSE N R. Women and autoimmune diseases[J]. Emerg Infect Dis, 2004, 10(11):2005-2011. DOI:10.3201/eid1011.040367 .
15	DUBOIS E L, HOROWITZ R E, DEMOPOULOS H B, et al. NZB/NZW mice as a model of systemic lupus erythematosus[J]. JAMA, 1966, 195(4):285-289. DOI:10.1001/jama. 1966. 03100040091025 .
16	HENDRIKSEN L C, VAN DER LINDEN P D, LAGRO-JANSSEN A L M, et al. Sex differences associated with adverse drug reactions resulting in hospital admissions[J]. Biol Sex Differ, 2021, 12(1):34. DOI:10.1186/s13293-021-00377-0 .
17	ZHAO H, DIMARCO M, ICHIKAWA K, et al. Making a 'sex-difference fact': ambien dosing at the interface of policy, regulation, women's health, and biology[J]. Soc Stud Sci, 2023, 53(4):475-494. DOI:10.1177/03063127231168371 .
18	Food and Drug Administration. FDA Drug Safety Communication: FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR[EB/OL]. (2013-05-14)[2025-02-25]. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-approves-new-label-changes-and-dosing-zolpidem-products-and.
19	RIDKER P N, COOK N R, LEE I M. A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women[J]. J Vasc Surg, 2005, 42(1):179. DOI:10.1016/j.jvs.2005.04.009 .
20	ROSANO G M C, LEWIS B, AGEWALL S, et al. Gender differences in the effect of cardiovascular drugs: a position document of the Working Group on Pharmacology and Drug Therapy of the ESC[J]. Eur Heart J, 2015, 36(40):2677-2680. DOI:10.1093/eurheartj/ehv161 .
21	KARP N A, MASON J, BEAUDET A L, et al. Prevalence of sexual dimorphism in mammalian phenotypic traits[J]. Nat Commun, 2017, 8:15475. DOI:10.1038/ncomms15475 .

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