实验动物与比较医学 ›› 2021, Vol. 41 ›› Issue (6): 505-514.DOI: 10.12300/j.issn.1674-5817.2021.056

• 人类疾病动物模型专题 • 上一篇    下一篇

卵巢早衰动物模型构建方法及比较研究进展

李虹璇1, 李思慧1, 冯嘉欣1, 唐凯2, 卢蕊1, 韩丝银1   

  1. 1.广西中医药大学基础医学院, 南宁 530200;
    2.广西中医药大学骨伤学院, 南宁530200
  • 收稿日期:2021-03-16 修回日期:2021-07-21 出版日期:2021-12-25 发布日期:2021-12-29
  • 作者简介:李虹璇(2001—), 女, 本科在读, 中医学专业。E-mail: 3385874884@qq.com
  • 基金资助:
    2020年国家级大学生创新创业训练计划项目(202010600030)

Construction Methods and Comparative Research Progress of Premature Ovarian Failure Animal Models

LI Hongxuan1, LI Sihui1, FENG Jiaxin1, TANG Kai2, LU Rui1, HAN Siyin1   

  1. 1. Basic Medical College, Guangxi University of Chinese Medicine, Nanning 530200, China;
    2. College of Bone Trauma, Guangxi University of Chinese Medicine, Nanning 530200, China
  • Received:2021-03-16 Revised:2021-07-21 Online:2021-12-25 Published:2021-12-29

摘要: 目前卵巢早衰动物模型的构建因素主要包括医源、免疫、遗传、代谢、环境等,根据这些因素构建的动物模型各有特点。本文综述了不同因素在构建卵巢早衰动物模型方面的作用和效果,以期为不同需要的研究者提供有用的建模信息。

关键词: 卵巢早衰, 动物模型, 因素, 比较

Abstract: Currently, the factors associated with premature ovarian failure animal models mainly include iatrogenic, immune, genetic, metabolic, and environmental factors. The animal models constructed based on these factors have their own characteristics. Here the construction methods and comparison of animal models of premature ovarian failure have been reviewed to provide useful modeling information for researchers with different needs.

Key words: Premature ovarian failure, Animal model, Factor, Comparison

中图分类号: