Laboratory Animal and Comparative Medicine ›› 2019, Vol. 39 ›› Issue (2): 163-168.DOI: 10.3969/j.issn.1674-5817.2019.02.017

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Research Progress of Rabbit VX2 Tumor Model

MI Jin-xia1,2, FANG Zhao-qin1   

  1. 1. School of Basic Medical Science;
    2. Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • Received:2018-10-09 Online:2019-04-25 Published:2021-01-29

Abstract: The rabbit VX2 tumor model is commonly used as a xenograft tumor model in large animals, which is also widely used in surgical operation, imageology and interventional therapy because of its body type and easy replication. The methods of establishing rabbit VX2 tumor model include injection of cell suspension and inoculation of tumor tissue block. The tumor models can be established differently depending on the site of the transplant. Researchers can select suitable tumor models for their own purposes. With the popularity of imaging equipment and the application of the emerging local treatment methods, more and more studies have been conducted using the rabbit VX2 tumor model. This paper reviewed the source of VX2 cells, biological characteristics, methods of tumor models and research applications.

Key words: Rabbit, VX2, Tumor, Model

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