Comparison on Anesthetic Effect of Intravenous Pentobarbital Sodium or Isoflurane Anesthesia in Mini-pig

doi:10.3969/j.issn.1674-5817.2013.03.012

Abstract

Abstract: Objective To observe the anesthetic effect of pentobarbital sodium iv or isoflurane anesthesia on mini-pig. Methods A total of 10 healthy Bama mini-pigs were equally randomized into two groups. One group was administered with pentobarbital sodium intravenously,and the other group was administered with isoflurane . Changes in narcotic indicators were observed. Results There was no significant difference in the number, body weight, anesthesia performing hours, the adverse reaction rate, SPO₂and pH value between the two groups (P>0.05), but both groups had significant difference in the onset time of anesthesia, postoperative recovery time, the number of cases of intraoperative restlessness, MAP and HR (P<0.05) between the two groups. Conclusion Anesthetic dose of sodium pentobarbital needs to be added during the experiment, while isoflurane anesthesia has better postoperative analgesic effect and less side effects, being a safe and effective analgesic option for different experiments.

Key words: Intravenous anesthesia, Inhalational anesthesia, Mini pig

CLC Number:

Q95-33

CAI Li-ping, YU Chen-lin, ZHAO Shan-min, TANG Qiu. Comparison on Anesthetic Effect of Intravenous Pentobarbital Sodium or Isoflurane Anesthesia in Mini-pig[J]. Laboratory Animal and Comparative Medicine, 2013, 33(3): 222-224.

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