Laboratory Animal and Comparative Medicine ›› 2022, Vol. 42 ›› Issue (1): 68-73.DOI: 10.12300/j.issn.1674-5817.2021.097

• Animal Models of Human Diseases • Previous Articles     Next Articles

Advances in Animal Models and Evaluation Methods of Pain and Depression Comorbidity

Renke HE1,2(), Cheng LU1,2, Wei CHEN1,2, Mengya WANG1, Aiping XU1()   

  1. 1.Cell Electrophysiology Laboratory, Wannan Medical College, Wuhu 241002, China
    2.Rising-Star Group, Wannan Medical College, Wuhu 241002, China
  • Received:2021-05-16 Revised:2021-08-03 Online:2022-02-25 Published:2022-02-25
  • Contact: Aiping XU

Abstract:

Comorbidity of pain and depression is a common health problem that seriously affects the physical and psychological health of patients. However, the pathogenesis of these symptoms remains unclear. To comprehensively understand the mechanisms and treatments of pain and depression comorbidity, this review summarizes the establishment of related animal models and behavioral evaluation methods of pain and depression comorbidity at home and abroad.

Key words: Comorbid pain, Depression, Animal model, Evaluation

CLC Number: