›› 2010, Vol. 30 ›› Issue (2): 132-135.

• 论文 • 上一篇    下一篇

一例藏酋猴创伤所致多器官功能衰竭的病理学观察

  

  1. 川省医学科学院·四川省人民医院实验动物研究所,成都 610212
  • 收稿日期:2009-10-15 出版日期:2010-02-28 发布日期:2010-02-28

Case Report on Pathological Observation of Multiple System Organ Failure Caused by Wound in Macaca thibetana

  1. Institute of Laboratory Animal of Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital Chengdu 610212
  • Received:2009-10-15 Online:2010-02-28 Published:2010-02-28

摘要: 目的 为探明藏酋猴创伤所致多器官功能衰竭的致病机理.方法 对一例实验藏酋猴因创伤所致多器官功能衰竭的病例进行了系统的病理学观察.结果 藏酋猴的剖检病变主要表现为肝脏肿大,肺萎缩,头部皮下组织大面积出血、坏死,腋下淋巴结、肠系膜淋巴结水肿.病理组织学表现为全身各组织器官不同程度的水肿、变性、坏死,尤以心,肺、肝、肾、肠和脑的病变较为明显.结论 颅外组织损伤易导致多器官功能衰竭.

关键词: 藏酋猴, 多器官功能衰竭, 病理学

Abstract: Objective To explore the pathogenic mechanism of multiple system organ failure (MSOF) caused by extracranial tissue injury. Methods A Macaca thibetanas dead by extracranial tissue injury was pathologically examed. Results Gross pathology shows that there is swelling in the liver;atrophy of lung; hemorrhage and necrosis in subcutaneous tissue of head; edema in oxter lymph node and mesenterium lymph node. Histopathological examination shows that there is edema, degeneration and necrosis in many organs. The pathological changes of heart, lung, liver, kidney, intestine and brain is very distinct. Conclusion Extracranial tissue injury can cause many organ failure in Macaca speciose thibetanasare.

Key words: Macaca thibetana, Multiple system organ failure, Pathology