›› 2010, Vol. 30 ›› Issue (2): 129-131.

• 论文 • 上一篇    下一篇

“优化”原则在保健食品功效研发试验中的应用

  

  1. 湖北省预防医学科学院,武汉 430079
  • 收稿日期:2009-09-24 出版日期:2010-02-28 发布日期:2010-02-28

Application of Refinement Principle in Consumer Health Food Function Accessment

  1. Hubei Academy of Preventive Medicine, Wuhan 430079, China
  • Received:2009-09-24 Online:2010-02-28 Published:2010-02-28

摘要: 目的 探讨“优化”方法在保健食品研发过程中应用.方法 在事先调研受试品成分的基础上,采用“优化”设计的方法,利用实验中有共性的程序和个性特点来进行组合式设计的方法,对某受试的保健食品进行缓解疲劳和增强免疫功能的8项指标试验.结果 (1)只采用了120只小鼠,获得受试品对小鼠机体8项影响作用的信息.(2)初步判断产品具有缓解疲劳和增强免疫的作用.结论 采用实验方案设计和实验指标选定的优化方法,可以用少量的动物获得到研发过程所需的更多的信息.

关键词: 3R, 优化, 保健食品, 功效实验

Abstract: Objective To find out the application value of refinement in consumer health food .Methods Based on the analysis result of contents of the tested samples, eight parameters including fatigue relief and increasing immune function were accessed by adopting “refinement” methods, in accordance with general procedure and specifically designated principle. Results (1) The data about fatigue relief and increasing immune function were collected by the study carried on 120 mice which is less than common using. (2) Those health food show the good effect on fatigue relief and increasing immune in primary study. Conclusion The refinement method combined with designed requirement method could obtain necessary information with less numbers of laboratory animals.

Key words: Refinement, Health food, Functionality experiment