实验动物与比较医学 ›› 2017, Vol. 37 ›› Issue (4): 283-287.DOI: 10.3969/j.issn.1674-5817.2017.04.005

• 论著 • 上一篇    下一篇

成年实验兔群体饲养的可行性考察

李彩云1,2, 姜子睿1,2, 潘学营1,2, 宋征1,2, 常艳1,2   

  1. 1.国家上海新安全评价研究中心, 上海 201203;
    2.上海益诺思生物技术有限公司, 上海 201203
  • 收稿日期:2017-01-16 出版日期:2017-08-25 发布日期:2017-08-25
  • 作者简介:李彩云(1983-),女,兽医学硕士,助理研究员。E-mail:cyli@ncdser.com
  • 基金资助:
    上海市研发公共服务平台项目(15DZ2290300)

The Feasibility of Social Housing for Adult Laboratory Rabbits

LI Cai-yun1,2, JIANG Zi-rui1,2, PAN Xue-ying1,2, SONG Zheng1,2, CHANG Yan1,2   

  1. 1. National Shanghai Center for New Drug Safety Evaluation and Research, Shanghai 201203, China;
    2. Shanghai Innostar Bio-tech Co. Ltd., Shanghai 201203, China
  • Received:2017-01-16 Online:2017-08-25 Published:2017-08-25

摘要: 目的 考察成年实验兔群体饲养的可行性。方法 取6月龄新西兰白兔38只,雌雄各半,单笼饲养,群养前1 d测定摄食量和体质量,然后按性别分为2组,每组19只,分为8个群养笼,其中,5个群养笼2只/笼,3个群养笼3只/笼,群养7 d,观察实验兔摄食量、体质量、打斗及受伤情况,随后继续单笼饲养至28 d。结果 成年雌兔群养后比群养前摄食量下降,群养影响动物体质量的正常增长; 且在群养第1日的观察中打斗频率较高,社会等级确立后打斗减少或消失,动物无明显受伤。成年雄兔群养期间摄食量降低明显,并造成体质量下降,打斗在整个群养期间持续发生,导致动物明显的受伤甚至死亡。恢复单笼饲养后,摄食量和体质量增长逐渐恢复。结论 成年雌兔经过群养初期的适应后可适当进行群体饲养,成年雄兔群养不可行。

关键词: 实验兔, 群体饲养, 配对饲养

Abstract: Objective To study the feasibility of social housing for adult laboratory rabbits. Methods Totally 38 New Zealand white rabbits aged at 6 months with 19 males and 19 females were single housed. Food intake and body weight were observed one day prior to social housing, then the rabbits were divided into 2 groups (19 male, 19 female), each group respectively housed in 8 cages (5 cages with 2 rabbits, 3 cages with 3 rabbits) for 7 days, food intake, body weight, fighting and injury were observed during 7 days social housing, and then single housed for 21 days. Results The food intake of female rabbits was decreased compared with that of being single housed, the normal growth of body weight was affected; high fighting frequency was observed at the first day of social housing, fighting frequency reduced or stopped after social hierarchy established; no obvious injuries were observed. The amount of food intake and body weight were reduced significantly for adult male rabbits during social housing, frequent and continuous fights were observed that caused serious injuries even death. Conclusions Adult female rabbits can be social housed under proper nursing by animal care staff during the initial stage of social housing, social housing for adult male rabbits is infeasible.

Key words: Laboratory rabbits, Social housing, Pair housing

中图分类号: