doi:10.3969/j.issn.1674-5817.2011.05.004

[1] Hong W, Yang ZZ, Ai DW, et al.Researches on Chinese laboratory miniature pigs, China-EU Animal Biotechnology Conference Proceedings[M]. Shenzhen, 2000,11-13.
[2] Ellegaard L, Jorgensen KD, Klast rup S, et al. Haematologic and clinical chemical values in 3 and 6 months old G^TMtt ingen minipigs[J]. Scand J Lab Anim Sci, 1995, 22: 239-248.
[3] Jorgensen KD, Ellegaard L, Klastrup S, et al.Haematological and clinical chemical values in pregnant and juvenile G^TMttingen minipigs[J]. Scand J Lab Anim Sci, 1998, 25: 181-190.
[4] 刘亚千, 李春海, 陈华, 等. 三个品系小型猪部分血液生化指标比较[J]. 实验动物科学, 2007, 24(5):24-26.
[5] Stanton HC, Mersmann HJ.Swine in Cardiovascular Research [M]. Boca Raton: CRC Press,1986.
[6] Smith AC, Swindle MM. Preparation of swine for the laboratory[J]. ILAR, 2006, 47:4, 358-363.
[7] Puppione DL, Whitelegge JP, Yam LM, et al.Mass spectral analysis of pig (Sus scrofa) apo HDL: identification of pig apoA-II, a dimeric apolipoprotein[J]. Comp Biochem Physiol, 2005, 141:89-94.
[8] Bergen WG, Mersmann HJ.Comparative aspects of lipid metabolism: impact on contemporary research and use of animal models[J]. J Nutr, 2005, 135:2499-2502.
[9] 陈华. 小型猪动脉粥样硬化模型[J]. 中国实验动物学报, 2008, 16(5):376-380.
[10] Jay TR,Heald KA, Carless NJ, et al.The distribution of porcine pancreatic beta-cells at ages 5, 12 and 24 weeks[J]. Xenotransplantation, 1999, 6:131-140.
[11] Lewis DF, Ioannides C, Parke DV, et al.Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP 3A activity and hepatomegaly associated with increased DNA synthesis[J]. J Steroid Biochem Mol Biol, 2000, 74(4):179-185.
[12] Smith DA, Jones BC.Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes[J]. Biochem Pharmacol, 1992, 44:2089-2098.
[13] Guengerich FP.Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene[J].Chem Res Toxicol,1995a, 3:363-371.
[14] Guengerich FP.Human cytochrome P-450 enzymes, in Cytochrome P-450 (Ortiz de Montellano PR ed)[M]. New York: Plenum, 1995. 473.
[15] Maedaa K, Yasunari K, Eisuke FS, et al.Enhanced oxidative stress in neutrophils from hyperlipidemic guinea pig[J]. Atherosclerosis, 2005:1-6.
[16] Jian L, Yong L, Jiang WZ, et al.Characterization of drug metabolizing activities in Chinese Bama miniature pigs(Sus Scrofa Domestica): comparison with human analogs[J].Comp Med 2006, 56(4): 269-273.
[17] Peter JT, Ruth EL, Michael A, et al.An obesity-associated gut microbiome with increased capacity for energy harvest[J].nature, 444, 1027-1031.
[18] Miller ER,Ullrey DE.The pig as a model for human nutrit ion[J]. Annu Rev Nutr, 1987, 7:361-382.
[19] Pang X, Hua X, Yang Q, et al.Inter-species transplantation of gut microbiota from human to pigs[J]. ISME J. 2007, 1(2):156-62.
[20] Swindle MM.Swine in the Laboratory (Surgery, Anesthesia, Imaging, and Experimental Techniques) [M]. 2nd ed. Boca Raton: CRC Press, 2007.
[21] Bellinger DA, Merricks EP, Nichols TC, et al.Swine models of type 2 diabetes mellitus: insulin resistance, glucose tolerance, and cardiovascular complications[J]. ILAR J, 2006, 47(3):243-258.
[22] Phillips RW, Westmoreland N, Panepinto LM, et al.Dietary effects on metabo lism of Yucatan miniature swine selected for low and high glucose utilization[J]. J Nutr, 1982, 112:104-111.
[23] Swindle MM, Thompson RP, Carabello BA, et al.Congenital cardiovascular disease. In : Swindle MM ed. Swine as Models in Biomedical Research [M] . Ames IA: Iowa State University Press ,1992, 176-1841.
[24] Mitchell SE, JH Anderson, MM Swindle, et al.Atrial septostomy: Stationary angioplasty balloon technique. Experimental work and preliminary clinical applications[J]. Podiatr Cardiol, 1994, 15(1):1-7.
[25] Hsu FS, Du SJ.Congenital heart diseases in swine[J]. Vet Pathol, 1982, 19:676-686.
[26] Dominique C, Joachim C, Patricia R, et al.Echocardiographic analysis with a two-dimensional strain of chronic myocardialischemia induced with ameroid constrictor in the pig[J].Interact CardioVasc Thorac Surg, 2010, 10:689-693.
[27] 刘建勋, 于震, 李欣志. 疾病模型动物拟临床研究概念的形成及其应用[J].中药药理与临床, 2007; 23(5):207-209.
[28] 刘涛, 刘正湘, 文莎, 等. 小型猪急性心肌梗死模型的建立及其评价[J]. 中国比较医学杂志, 2009, 19(3):10-12.
[29] Odenstedt J, Mansson C, Jansson SO, et al.Endocardial electromechanical mapping in a porcine acute infarct and reperfusion model evaluating the extent of myocardial ischemia[J]. J Invasive Cardiol, 2003, 15(9):497-501.
[30] 关启刚, 程颖, 曾定尹. 炎症因子介导的小型猪冠状动脉痉挛模型的构建.络病学基础与临床研究[M].《络病学基础与临床研究(2)——第二届国际络病学大会论文集》. 2006, 166-199.
[31] 袁晋青, 高润霖, 宋来凤, 等.小型猪冠状动脉置入过大直径支架建立再狭窄动物模型[J]. 中国循环杂志, 1999, 14(5):283-285.
[32] Yin W, Liao D, Xi S, et al.NO-1886 (ibrolipim) decreases ectopic lipids deposition, protects pancreatic ? cell in high fat, high sucrose diet-fed mini-pig[J]. J Endocrinol, 2004, 180:399-408.
[33] 管耘园, 卢辉, 盛臻强, 等. 过大球囊扩张配合高脂饮食建立小型猪冠状动脉粥样硬化模型[J]. 江苏医药, 2006, 32(4):372-373.
[34] Holvoet P, Theilmeier G, Shivalkar B, et al.LDL hypercholes terolemia is associated with accumulation of oxidized LDL,atherosclerotic plaque growth, and compensatory vessel enlargement in coronary arteries of miniature pigs[J]. Arteriosclerosis, Thrombosis, and Vascular Biology, 1998, 18:415-422.
[35] 姚峰, 王宗保, 谭翔文, 等. 贵州小型猪2 型糖尿病动物模型的建立[J]. 南华大学学报医学版, 2004, 32(3):294-297.
[36] 张永斌, 邹移海, 刘晓秋, 等.小型猪糖尿病性勃起功能障碍模型的建立[J]. 广东医学, 2010, 31(9):1094-1096.
[37] Zambraski EJ, Ciccone CD.Effects of aortic constriction and renal denervation in DOCA-hypertensive swine[J]. Am J Physiol, 1987, 253:1223-1231.
[38] Loukanov T, Geiger R, Agrawal R.Animal models related to congenital heart disease and clinical research in pulmonary hypertension[J]. Cardiology, 2010, 116(1):18-25.
[39] Hannon JP.Hemorrhage and hemorrhagic shock in swine. A review[M]. Ames, Iowa: Iowa State University Press, 1992. 197-245.
[40] 朱海涛, 张礼均, 李飞, 等. 模拟急进高原环境下小型猪创伤性脑出血模型的建立[J]. 第三军医大学学报, 2011, 33(9):869-873.
[41] 董晓英, 牛欣, 杨学智, 等. 小型猪脉滑变模型的建立与评价[J]. 北京中医药大学学报, 2009, 32(5):324-330.
[42] 李欣志, 马晓斌, 李磊, 等. 小型猪冠心病模型痰瘀互结证候诊断与评分[J]. 中国中医基础医学杂志, 2009, 15(11):825-827.
[43] Umeyama K, Watanabe M, Saito H, et al.Dominant-negative mutant hepatocyte nuclear factor 1alpha induces diabetes in transgenic-cloned pigs[J]. Transgenic Research, 2009, 5:697-706.
[44] Renner S, Fehlings C, Herbach N,et al.Glucose intolerance and reduced proliferation of pancreatic ?-cells in transgenic pigs with impaired GIP function[J]. Diabetes, 2010, 59(5):1228-1238.

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	JIAO Qingzhen, WU Guihua, TANG Wen, FAN Fan, FENG Kai, YANG Chunxiang, QIAO Jian, DENG Sufang. Dynamic Monitoring and Analysis of Ammonia Concentration in Laboratory Animal Facilities Under Suspension of Heating Ventilation and Air Conditioning System [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 490-495.
[2]	LIU Wentao, LUO Yanhong, LONG Yongxia, LUO Qihui, CHEN Zhengli, LIU Lida. Common Environmental Problems and Testing Experiences in Laboratory Animal Facilities in Sichuan Province [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 483-489.
[3]	ZHAO Xin, WANG Chenxi, SHI Wenqing, LOU Yuefen. Advances in the Application of Zebrafish in the Research of Inflammatory Bowel Disease Mechanisms and Drug Development [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 422-431.
[4]	GONG Leilei, WANG Xiaoxia, FENG Xuewei, LI Xinlei, ZHAO Han, ZHANG Xueyan, FENG Xin. A Mouse Model and Mechanism Study of Premature Ovarian Insufficiency Induced by Different Concentrations of Cyclophosphamide [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 403-410.
[5]	LIN Zhenhua, CHU Xiangyu, WEI Zhenxi, DONG Chuanjun, ZHAO Zenglin, SUN Xiaoxia, LI Qingyu, ZHANG Qi. Evaluation of the Safety and Efficacy of Bone Cement in Experimental Pigs Using Vertebroplasty [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 466-472.
[6]	JIANG Juan, SONG Ning, LIAN Wenbo, SHAO Congcong, GU Wenwen, SHI Yan. Comparison of Histopathological and Molecular Pathological Phenotypes in Mouse Models of Intrauterine Adhesions Induced by Two Concentrations of Ethanol Perfusion [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 393-402.
[7]	LIU Yueqin, XUE Weiguo, WANG Shuyou, SHEN Yaohua, JIA Shuyong, WANG Guangjun, SONG Xiaojing. Observation of Digestive Tract Tissue Morphology in Mice Using Probe-Based Confocal Laser Endomicroscopy [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 457-465.
[8]	ZHENG Qingyong, YANG Donghua, MA Zhichao, ZHOU Ziyu, LU Yang, WANG Jingyu, XING Lina, KANG Yingying, DU Li, ZHAO Chunxiang, DI Baoshan, TIAN Jinhui. Recommendations for Standardized Reporting of Systematic Reviews and Meta-Analysis of Animal Experiments [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 496-507.
[9]	WANG Tingjun, LUO Hao, CHEN Qi. Discussion on AI-Based Digital Upgrade and Application Practice of Laboratory Animal Centers [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 473-482.
[10]	WANG Jiaoxiang, ZHANG Lu, CHEN Shuhan, JIAO Deling, ZHAO Heng, WEI Taiyun, GUO Jianxiong, XU Kaixiang, WEI Hongjiang. Construction and Functional Validation of GTKO/hCD55 Gene-Edited Xenotransplant Donor Pigs [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 379-392.
[11]	QIN Chao, LI Shuangxing, ZHAO Tingting, JIANG Chenchen, ZHAO Jing, YANG Yanwei, LIN Zhi, WANG Sanlong, WEN Hairuo. Study on the 90-day Feeding Experimental Background Data of SD Rats for Drug Safety Evaluation [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 439-448.
[12]	LIU Kun, LAN Qing, YI Bing, XIE Xiaojie. Key Challenges and Mitigation Strategies for Animal Pregnancy in Non-clinical Reproductive Toxicity Testing of Drugs [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 449-456.
[13]	. [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 508-514.
[14]	CHEN Ziyi, SUN Hongyan, KANG Pinfang, WU Wenjuan. Research Advances in Animal Experimental Models of Pulmonary Hypertension [J]. Laboratory Animal and Comparative Medicine, 2025, (): 1-12.
[15]	XU Yingtao, WANG Mengmeng, LIN Ping, CHI Haitao, WANG Yi, BAI Ying. Exosomes Improve Ischemic Stroke by Regulation of Ferroptosis Through the NRF2/SLC7A11/GPX4 Pathway in Mice [J]. Laboratory Animal and Comparative Medicine, 2025, (): 1-11.