Liquichip Technology and Its Application in Detection of Protein and Nucleic Acid

doi:10.3969/j.issn.1674-5817.2015.01.016

Abstract

Abstract: Liquichip is a new type of detection technology developed in the 1990s, which is integrated with flow cytometry, laser technology and digital signal processing. Compared with the traditional clinical detection methods, the main advantages are the high-throughput, high-sensitivity, high reproducibility, wide detection range, fast response, and only small amount of testing sample wanted. Luminex has two core technologies: xMAP^® technology and xTAG^® Technology. xMAP^® technology utilizing an antigen-antibody reaction principle, can be used for the detection of proteins and nucleic acids. xTAG^® technology can be used for a number of genomic assay formats such as gene expression analysis, microRNA analysis, single nucleotide polymorphism (SNP)analysis, specific sequence detection and other applications.

Key words: Luminex, Liquichip, Proteins and nucleic acids, Detection

CLC Number:

Q95-33

LIU Chun-mei, WEI Xiao-feng, GAO Cheng. Liquichip Technology and Its Application in Detection of Protein and Nucleic Acid[J]. Laboratory Animal and Comparative Medicine, 2015, 35(1): 76-81.

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