Laboratory Animal and Comparative Medicine ›› 2018, Vol. 38 ›› Issue (2): 160-164.DOI: 10.3969/j.issn.1674-5817.2018.02.016

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Research Progress on Infection Mechanism and Diagnostic Methods of Ectromelia Virus

ZHOU Jie, ZHAO Li-juan, TAO Ling-yun, HU Jian-hua, GAO Cheng   

  1. Shanghai Laboratory Animal Research Center,Shanghai,201203 China
  • Received:2017-08-17 Online:2018-04-25 Published:2018-04-25

Abstract: The paper mainly reviewed the infection and spread mechanisms of Ectromelia virus (ECTV) in animals,including natural disease resistance mechanism of the mice,the body's immune response and pathogenic mechanism of virus infection.Furthermore,we described the animal experiments,pathological diagnosis,serological methods,nucleic acid methods of ECTV and their advantages and disadvantages.This article can help to understand infection mechanism and different diagnostic methods of ECTV,which may contribute to control the spread of ECTV.

Key words: Ectromelia virus (ECTV), Infection mechanism, Immune response, Detection

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