The Research Progress on Simian Cytomegalovirus

doi:10.3969/j.issn.1674-5817.2014.03.016

Abstract

Abstract: Simian cytomegalovirus(SCMV) were the prototypic members of the beta herpesvirus subgroup, a group of DNA virus with segment rounded. Like all herpesvirus, they shared the similar structure characteristics, and could initiate persistent latent infection. Recently, SCMV were wildly concerned as the best suited model for human cytomegalovirus (HCMV) research, and the study of infection route, pathogenic mechanism and diagnosis and treatment for SCMV could lay a foundation for those of HCMV. This article reviewed the discovery , classification, biological characteristics, infection characteristics and immunological response, detections of SCMV, vaccines reserch and development prospects so as to provide some useful insights for researchers.

Key words: Simian Cytomegalovirus, Biological characteristics, Detection, Vaccines

CLC Number:

Q95-33

WANG Sha-sha, HE Zheng-ming. The Research Progress on Simian Cytomegalovirus[J]. Laboratory Animal and Comparative Medicine, 2014, 34(3): 242-248.

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