Laboratory Animal and Comparative Medicine ›› 2014, Vol. 34 ›› Issue (1): 46-49.DOI: 10.3969/j.issn.1674-5817.2014.01.009

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Analysis on Femur Bone Parameters in Female Mice by Using Micro-CT

GENG Qin, ZHU Miao-xin, SUN Lei, CUI Yong-qi, KONG Han-wei, YAO Ming, LIU Lei   

  1. Key Laboratory of Oncogenes and Related Genes of Shanghai Cancer Institute, Shanghai 200032, China
  • Received:2013-08-08 Online:2014-02-25 Published:2014-02-25

Abstract: Objective To obtain femur bone datas about female BALB/c-nu/nu and BALB/c mice by using micro-CT. Methods The femur from fifteen female nude mice with BALB/c background and BALB/c mice respectively, aged 10-12weeks, were scanned with micro-CT. Results The parameters of female BALB/c-nu/nu and BALB/c mice femur bone were detected by using micro-CT, there are differences of femur bone in some parameters between BALB/c-nu/nu and BALB/c mice. In the vortical bone, there is significant difference in BV/TV. In the trabecular bone, BV/TV, BS/TV and BMD have significant difference. Conclusions Micro-CT can be used for quantitative analysis of mice femur bone parameters.

Key words: Micro-CT, Femur, Mice, Female

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