[1] LI A, PENG W X, XIA X D, et al.Endothelial-to-mesenchymal transition: a potential mechanism for atherosclerosis plaque progression and destabilization[J]. DNA Cell Biol, 2017, 36(11):883-891. DOI:10.1089/dna.2017.3779. [2] LOVISA S, ZEISBERG M, KALLURI R.Partial epithelial-to-mesenchymal transition and other new mechanisms of kidney fibrosis[J]. Trends Endocrinol Metab, 2016, 27(10):681-695. DOI:10.1016/j.tem.2016.06.004. [3] CHEN P Y, QIN L, BAEYENS N, et al.Endothelial-to-mesenchymal transition drives atherosclerosis progression[J]. J Clin Invest, 2015, 125(12):4514-4528. DOI:10.1172/jci82719. [4] QI Z, LI M, ZHU K, et al.Si-Miao-Yong-An on promoting the maturation of Vasa Vasorum and stabilizing atherosclerotic plaque in ApoE-/-mice: an experimental study[J]. Biomed Pharmacother, 2019, 114:108785. DOI:10.1016/j.biopha.2019.108785. [5] BRAVI L, MALINVERNO M, PISATI F, et al.Endothelial cells lining sporadic cerebral cavernous malformation cavernomas undergo endothelial-to-mesenchymal transition[J]. Stroke, 2016, 47(3):886-890. DOI:10.1161/strokeaha.115.011867. [6] KOSTINA A S, USPENSKY V Е, IRTYUGA O B, et al.Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve[J]. Biochim Biophys Acta, 2016, 1862(4):733-740. DOI:10.1016/j.bbadis.2016.02.006. [7] NAKANO M, FUKUMOTO Y, SATOH K, et al.OX40 ligand plays an important role in the development of atherosclerosis through Vasa vasorum neovasculari-zation[J]. Cardiovasc Res, 2010, 88(3):539-546. DOI:10.1093/cvr/cvq211. [8] OLOFSSON P S, SÖDERSTRÖM L A, WÅGSÄTER D, et al. CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice[J]. Circulation, 2008, 117(10):1292-1301. DOI:10.1161/circulationaha.107. 699173. [9] JEON H J, CHOI J H, JUNG I H, et al.CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice[J]. Circulation, 2010, 121(9):1124-1133. DOI:10.1161/circulationaha.109.882704. [10] WENG J Y, WANG C P, ZHONG W, et al.Activation of CD137 signaling promotes angiogenesis in atherosclerosis via modulating endothelial Smad1/5-NFATc1 pathway[J]. J Am Heart Assoc, 2017, 6(3): e004756. DOI:10.1161/jaha.116.004756. [11] WANG X, ABRAHAM S, MCKENZIE J A G, et al. LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling[J]. Nature, 2013, 499(7458):306-311. DOI:10.1038/nature12345. [12] VAN DER VEKEN B, DE MEYER G R Y, MARTINET W. Axitinib attenuates intraplaque angiogenesis, haemorrhages and plaque destabilization in mice[J]. Vascul Pharmacol, 2018, 100:34-40. DOI:10.1016/j.vph.2017.10.004. [13] JOO S P, LEE S W, CHO Y H, et al.Vasa vasorum densities in human carotid atherosclerosis is associated with plaque development and vulnerability[J]. J Korean Neurosurg Soc, 2020, 63(2):178-187. DOI:10.3340/jkns.2019.0077. [14] DE VRIES M R, QUAX P H. Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization[J]. Curr Opin Lipidol, 2016, 27(5):499-506. DOI:10.1097/mol.0000000000000339. [15] 翁嘉懿, 严金川, 陈瑶, 等. CD137-CD137L信号通路通过活化T细胞核因子c1促进小鼠动脉粥样硬化斑块内血管新生[J]. 中华心血管病杂志, 2016, 44(12):1040-1046. DOI:10.3760/cma.j.issn.0253-3758. 2016.12.010. [16] XIE Y, LIAO J, YU Y, et al.Endothelial-to-mesenchymal transition in human idiopathic dilated cardiomyopathy[J]. Mol Med Rep, 2018, 17(1):961-969. DOI:10.3892/mmr.2017.8013. https://pubmed.ncbi.nlm.nih.gov/29115553/ [17] ANBARA T, SHARIFI M, ABOUTALEB N.Endothelial to mesenchymal transition in the cardiogenesis and cardiovascular diseases[J]. Curr Cardiol Rev, 2020, 16(4):306-314. DOI:10.2174/1573403X15666190808100336. [18] LI H R, ZHAO Q F, CHANG L P, et al.LncRNA MALAT1 modulates ox-LDL induced EndMT through the Wnt/β-catenin signaling pathway[J]. Lipids Heal Dis, 2019, 18(1):62. DOI:10.1186/s12944-019-1006-7. |