一氧化氮对动物胚胎附植影响的研究

doi:10.3969/j.issn.1674-5817.2015.04.021

实验动物与比较医学 ›› 2015, Vol. 35 ›› Issue (4): 341-344.DOI: 10.3969/j.issn.1674-5817.2015.04.021

• 综述 • 上一篇

一氧化氮对动物胚胎附植影响的研究

魏东, 孙全文

河北北方学院实验动物中心, 张家口 075000

收稿日期:2015-05-31 出版日期:2015-08-25 发布日期:2015-08-25
作者简介:魏东(1971-), 男, 博士, 副研究员, 研究方向: 基础兽医学。E-mail: hbzjkwd@163.com

Effects of Nitric Oxide on Embryonic Implantation in Animals

WEI Dong, SUN Quan-wen

Laboratory Animal Center, Hebei North University, Zhangjiakou 075000, China

Received:2015-05-31 Online:2015-08-25 Published:2015-08-25

摘要/Abstract

摘要： 一氧化氮(NO)作为一种特殊的生物传递信号分子,日益受到生命科学各领域的普遍重视。机体内的NO由一氧化氮合酶催化合成,是动物体内发挥多种生物学效应的自由基,是一种重要的生物信使,它几乎对哺乳动物的所有系统都会产生一定的作用。近几年的研究结果表明, NO对动物胚胎附植发挥着重要作用。

关键词: 一氧化氮(NO), 胚胎附植, 一氧化氮合酶

Abstract: Nitric oxide (NO) is a special biological signal molecule, it is being paid attention to the life sciences in various fields. The NO of the organism is synthesized by catalysis of nitric oxide synthase(NOS). NO is a free radicals in body playing a variety of biological effects, and an important biological messenger producing certain effects in almost all systems of mammals. The recent researches show that NO plays an important role on animal embryo implantation.

Key words: Nitric oxide, Embryonic implantation, Nitric oxide synthase

中图分类号:

Q95-33

魏东, 孙全文. 一氧化氮对动物胚胎附植影响的研究[J]. 实验动物与比较医学, 2015, 35(4): 341-344.

WEI Dong, SUN Quan-wen. Effects of Nitric Oxide on Embryonic Implantation in Animals[J]. Laboratory Animal and Comparative Medicine, 2015, 35(4): 341-344.

参考文献

[1] Shakarjian MP,Bhatt P,Gordon MK,et al.Preferential expression of matrix metalloproteinase-9 in mouse skin after sulfur mustard exposure[J]. Appl Toxicol, 2006, 26(3):39-46.
[2] 刘建国, 王先.一氧化氮和细胞因子之间的相互调节作用[J]. 生理科学进展, 2000, 31(1):61-64.
[3] Tranguch S, Daikoku T, Guo Y, et al.Molecular complexity in establishing uterine receptivity and implantation[J]. Cell Mol Life Sci, 2005, 62(17):1964-1973.
[4] 罗扬. 活性氧与发育毒性研究进展[J]. 国外医学: 卫生学分册, 1997, 4(24):239-243.
[5] 朱猛进, 丁家桐, 刘红林. 一氧化氮(NO)对动物妊娠生理的调节[J]. 贵州畜牧兽医, 2000, 24(1):10-11.
[6] Ronaldo JD, Mateo MS.Arginine and omega3 fatty acids for enhancing reproductive performance of sows [D]. Lubbock: Texas Tech University, 2007.
[7] Mcknight JR, Satterfield MC, Jobgen WS, et al.Beneficial effects of L-arginine on reducing obesity: potential mechanisms and important implications for human health[J].Amino Acids, 2010, 39(2):349-357.
[8] Krumenacker JS, Katsuki S, Kots A, et al.Differential expression of genes involved in cGMP-dependent nitric oxide signaling in murine embryonic stem (ES) cells and ES cell-derived cardiomyocytes[J]. Nitric Oxide, 2006, 14(1): 1-11.
[9] Bazer FW, Wu Q, Spencer TE, et al.Novel pathways for implantation and establishment and maintenance of pregnancy in mammals[J]. Mol Hum Reprod, 2010, 16(3):135-152.
[10] Gouge RC, Marshburn P, Gordon BE, et al.Nitric oxide as a regulator of embryonic development[J]. Biol Reprod, 1998, 58(4):875-879.
[11] Sanyal M, Nay TC, Das C.Localization of nitric oxide synthase in human trophoblast cells: role of nitric oxide in trophoblast proliferation and differentiation[J]. Am J Reprod Immunol, 2000, 43(2):70-77.
[12] Novaro V, Pustovrh C, Colman-Leme A, et al.Nitric oxide induces gelatinase A(matrix metalloproteinase 2) during rat embryo implantation[J]. Fertil Steril, 2002, 78(6):1278-1287.
[13] 廖海艳, 王方剑, 薛立群.一氧化氮对小鼠胚胎附植影响的研究[J]. 湖南农业科学, 2010, (15):133-136.
[14] 廖海艳, 庄远红. 一氧化氮对小鼠胚胎附植期MMP-9表达的影响[J]. 湖南农业科学, 2013, (09):6-10.
[15] Novaro V, Gonzalez E, Jawerbaum A, et al.Nitric oxide synthase regulation during embryonic implantation[J]. Reprod Fertil, 1997, 9(5): 557-564.
[16] Zhang X, Wang HM, Lin HY, et al.Regulation of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) during mouse peri-implantation: role of nitric oxide[J]. Placenta, 2004, 25(4):243-252.
[17] Tranguch S, Steuerwald N, Huet-Hudson YM.Nitric oxide
synthase production and nitric oxide regulation of preimplantation embryo development[J]. Biol Reprod, 2003, 68(5):1538-1544.
[18] Chen HW, Jiang WS, Zeng CR.Nitric oxide as a regulator in preimplantation embryo development and apoptosis[J]. Fertil Steril, 2004, 75(6):l163-117l.
[19] Estevez AG, Kamaid A, Thompson JA, et al.Cyclic guanosine onophosphate (GMP) prevents expression of neuronal nitric oxide synthase and apoptosis in motor neurons deprived of trophic factors in rats[J].Neurosci Lett, 2002, 326(3): 201-205.
[20] Chwalisz K, Garfield RE.Role of nitric oxide in implantation and menstruation[J]. Hum Reprod, 2000, 15(3):96-111.
[21] Purceu TL,Given R, Chwalosz K, et al.Nitric oxide synthase distribution during implantation in the mouse[J].Mol Hum Repro, 1999, 5(5):467-475.
[22] Kim BH, Kim CH, Jung KY, et al.Involvement of nitric oxide during in vitro fertilization and early embryonic development in mice[J]. Arch Pharm Res, 2004, 27(1):86-93.
[23] Sengoku K, Takuma N, Horikawa M, et al.Requirement of nitric oxide for murine oocyte maturation, embryo development, and trophoblast outgrowth in vitro[J]. Mol Reprod Dev, 2001, 58(3):262-268.
[24] Barroso RP, Osuamkpe C, Nagamani M, et al.Nitric oxide inhibits development of embryos and implantation in mice[J]. Mol Hum Reprod, 1998, 4(5):503-507.
[25] Athanassakis I, Aifantis I, Baritakis S, et al.Nitric oxide production by pre-implantation embryos in response to embryotoxic factors[J]. Cell Physiol Biochem, 2000, 10(3):169-176.
[26] Ogando DG, Paz D, Cella M, et al.The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice[J]. Reproduction, 2003, 125(1):95-110.

一氧化氮对动物胚胎附植影响的研究

Effects of Nitric Oxide on Embryonic Implantation in Animals

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