›› 2007, Vol. 27 ›› Issue (4): 276-279.

• 论文 • 上一篇    下一篇

鼠诺沃克病毒特征及其检测技术

  

  1. 北京实验动物研究中心,北京 100012
  • 收稿日期:2007-01-22 出版日期:2007-04-30 发布日期:2007-04-30

Structural Character and Detective Techniques of Murine Norovirus

  1. Beijing Laboratory Animal Research Center, Beijing 100012,China
  • Received:2007-01-22 Online:2007-04-30 Published:2007-04-30

摘要: 鼠诺沃克病毒-1(MNV-1)是一个新认知的鼠病原体,可引起固有免疫系统应答组分缺陷鼠的致死性感染,是目前唯一一个能够在细胞以及小动物体中复制的诺沃克病毒.通过病毒分离、免疫组化、RT-PCR技术,均可检测鼠诺沃克病毒-1.

关键词: 鼠诺沃克病毒-1, 检测技术

Abstract: Murine Norovirus l(MNV-l) is a newly recognized pathogen of mice that causes lethal infection in mice deficient in components of the innate immune response. Moreover, the murine virus 1 is the only norovirus that can replicate in cell culture and in a small animal. Murine norovirus 1 is detected by virus isolation, immunohistochemistry method and RT-PCR technique.

Key words: Murine Norovirus 1, Detective Techniques