鼠诺沃克病毒特征及其检测技术

实验动物与比较医学 ›› 2007, Vol. 27 ›› Issue (4): 276-279.

鼠诺沃克病毒特征及其检测技术

北京实验动物研究中心，北京 100012

收稿日期:2007-01-22 出版日期:2007-04-30 发布日期:2007-04-30

Structural Character and Detective Techniques of Murine Norovirus

Beijing Laboratory Animal Research Center, Beijing 100012,China

Received:2007-01-22 Published:2007-04-30 Online:2007-04-30

摘要/Abstract

摘要： 鼠诺沃克病毒-1（MNV-1）是一个新认知的鼠病原体，可引起固有免疫系统应答组分缺陷鼠的致死性感染，是目前唯一一个能够在细胞以及小动物体中复制的诺沃克病毒.通过病毒分离、免疫组化、RT-PCR技术，均可检测鼠诺沃克病毒-1.

关键词: 鼠诺沃克病毒-1, 检测技术

Abstract: Murine Norovirus l(MNV-l) is a newly recognized pathogen of mice that causes lethal infection in mice deficient in components of the innate immune response. Moreover, the murine virus 1 is the only norovirus that can replicate in cell culture and in a small animal. Murine norovirus 1 is detected by virus isolation, immunohistochemistry method and RT-PCR technique.

Key words: Murine Norovirus 1, Detective Techniques

翟新验,卢胜明. 鼠诺沃克病毒特征及其检测技术[J]. 实验动物与比较医学, 2007, 27(4): 276-279.

DI Xin-Yan,LU Sheng-Ming. Structural Character and Detective Techniques of Murine Norovirus[J]. Laboratory Animal and Comparative Medicine, 2007, 27(4): 276-279.