›› 1997, Vol. 17 ›› Issue (1): 8-10.

• 论文 • 上一篇    下一篇

纤维蛋白特异性抗原的种属特异性初探

  

  1. 上海医药工业研究院,上海 200434
  • 收稿日期:1995-08-30 出版日期:1997-01-25 发布日期:2013-03-19

Differences of Specific Antigen of Fibrins among Different Kinds of Animals

  1. Shanghai Institute of Pharmaceutic Industry,Shanghai 200433
  • Received:1995-08-30 Online:1997-01-25 Published:2013-03-19

摘要: 以抗人纤维蛋白特异性单克隆抗体,用ELISA法测试它对一些种属动物的纤维蛋白的反应。结果表明,抗人纤维蛋白的特异性单抗与牛、犬、兔、大鼠有交叉反应,以牛、犬的反应较强,大鼠最弱,且这种反应不为纤维蛋白原的存在所影响,但该单抗与鸡的纤维蛋白无反应。

关键词: 抗人纤维蛋白单克隆抗体, 纤维蛋白, 酶联免疫吸附试验

Abstract: Monoclonal antibody 9B3(MA9B3) is specific for human fibrin. Its reactions with fibrins of some other kinds of animals were tested. The results indicated that MA9B3 cross-reacted with fibrins of ox, dog, rabbit and rat. The orders of strength are ox, dog, rabbit and rat. The reactions were not interfered by fibrinogen. However ,MA9B3 did not react with chicken fibrin.

Key words: Monoclonal antibody, Fibrin, ELISA