›› 2009, Vol. 29 ›› Issue (1): 61-65.

所属专题: 实验动物资源开发与利用

• 论文 • 上一篇    下一篇

家蚕作为模式生物在现代生物学中的应用

  

  1. 苏州大学基础医学与生物科学学院,苏州,215123
  • 收稿日期:2008-10-13 出版日期:2009-01-31 发布日期:2009-01-31
  • 基金资助:
    国家自然科学基金项目(30771632),国家重点基 础研究计划“973”项目(2005CB121000)

Application of Bombyx mori as Model Organism in Modern Biology

  1. School of Basic Medicine & Biological Science, Soochow University, Suzhou, 215123, China
  • Received:2008-10-13 Online:2009-01-31 Published:2009-01-31

摘要: 家蚕作为鳞翅目昆虫的典型代表和理想的生物学模型对动物科学的发展起到了巨大的推 动作用,其特殊突变已经成为现代遗传工程研究的优良材料。随着家蚕全基因组框架图和精细图 制作的完成,家蚕将成为后基因组时代生命科学研究领域较为理想的模式生物。本文综述了家蚕 对现代遗传学的贡献,分析了家蚕作为模式生物在发育生物学、生物反应器和基因组分子平台建 设等研究领域的现状,论述了家蚕作为模式生物的在现代生物学领域的应用前景。

关键词: 家蚕, 模式生物, 发育生物学, 生物反应器, 基因组, 应用

Abstract: Silkworm,i.e. Bombyx mori, as the typical representative of lepidopteran insect and the ideal biological model,has played a significant role in promoting the development of animal science, which specific mutation has already been the optimum material for the research on modern genetic engineering. With the accomplishment of the draft of the silkworm genome and the fine map, silkworm will further become a comparatively ideal model organism in the field of research on life sciences in postgenome era. This text summarized the silkworm’s contributions to the modem genetics; again, analyzed the status quo of silkworm as the model organism in researching realms of developmental biology, bioreactor, and the construction of molecular platform of genome and so forth; and finally, discussed the application of silkworm being the model organism in the field of Modem Biology.

Key words: Bombyx mori., Model of organism, Developmental biology, Bioreactor, Genome, Application