Laboratory Animal and Comparative Medicine ›› 2013, Vol. 33 ›› Issue (6): 452-457.DOI: 10.3969/j.issn.1674-5817.2013.06.008

Special Issue: 实验动物伦理与福利专辑

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The Breeding, Husbandry, Technique and Welfare of Zebrafish

CHANG Jia, PAN Xue-ying, LU Liang, CHANG Yan, MA Jing1,*   

  1. National Shanghai Center for New Drug Safety Evaluation and Research, China State Institute of Pharmaceutical Industry, Shanghai 201203, China
  • Received:2013-06-13 Online:2013-12-25 Published:2013-12-25

Abstract: Zebrafish as an ideal animal model was widely used in scientific experiments. In recent years, with the increase in its research and application, the number of zebrafish used is increasing. But the zebrafish‘s breeding management, operation and the welfare has less been reported, and also there is no SOP. To solve this problem, this article reviews the relevant laws and regulations, guidelines and literature, zebrafish‘s breeding management(Transportation, environmental conditions, equipment maintenance), operation (Breeding, identification mark, anesthesia and euthanasia) and the welfare has been discussed respectively. This paper aims to provide a relevant reference for other researchers, to protect and improve the welfare of zebrafish.

Key words: Zebrafish, Husbandry, Technique, Animal welfare