Laboratory Animal and Comparative Medicine ›› 2022, Vol. 42 ›› Issue (2): 166-170.DOI: 10.12300/j.issn.1674-5817.2021.078

Special Issue: 实验动物伦理与福利专辑

• Laboratory Animal Welfare and Ethics • Previous Articles    

Nursing Practice and Discussion of Electrode Implantation into Cerebral Cortex of Rhesus Monkey

Xibin XU(), Qing ZHU, En ZHANG()   

  1. State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China
  • Received:2021-04-07 Revised:2021-09-23 Online:2022-04-25 Published:2022-05-07
  • Contact: En ZHANG

Abstract:

The use of electrode implantation technology to explore the electrical activity of population neurons is crucial for brain and cognitive science, brain-like research and brain-computer interface technology research. This article introduces the nursing points and significance of electrode implantation in rhesus monkey cerebral cortex before, during and after operation. Preoperative care includes preoperative preparation, preoperative medication, cranial fixation, skin preparation, etc. Intraoperative care includes physiological index monitoring and cerebral cortex implantation surgery care, while postoperative care includes observation and monitoring, debridement and nutritional care. Doing a good job in the operation of electrode implantation into the cerebral cortex of rhesus monkeys can not only improve the success rate of the operation, use as few experimental animals as possible to obtain the data required for the experiment, but also reduce the pain and injury caused by the operation to the animals, which is of great significance for brain and cognitive science research and animal welfare protection.

Key words: Electrode implantation, Cortical surgery, Nursing, Laboratory animal welfare, Rhesus monkeys

CLC Number: