Laboratory Animal and Comparative Medicine ›› 2023, Vol. 43 ›› Issue (2): 180-185.DOI: 10.12300/j.issn.1674-5817.2022.142

• Animal Models of Human Diseases • Previous Articles     Next Articles

Research Progress on Influenza A Virus and Nervous System Disease of Human and Experimental Animals

Xiangrong DING1(), Shurui HUO2, Jiejie DAI1()()   

  1. 1.Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China
    2.Kunming Medical University, Kunming 650500, China
  • Received:2022-09-02 Revised:2022-12-17 Online:2023-04-25 Published:2023-05-16
  • Contact: Jiejie DAI

Abstract:

Influenza is a highly contagious disease that mainly affects the respiratory system and often leads to lung complications. Also it can cause a variety of very rare and serious neurological complications, including Guillain-Barre syndrome, transverse myelitis, meningoencephalitis and others. In recent years, neurological complications caused by influenza A virus have been reported in many countries and regions, and gradually attracted international attention. However, the pathogenesis of this complication remains unclear, and there are few related cases and animal experimental studies,and no specific treatment. Therefore, the authors summarized the study of neurological complications caused by influenza A virus in human and laboratory animals, in order to have a comprehensive understanding of the neurological diseases caused by influenza A virus.

Key words: Influenza A virus, Neurological complications, Animal experiment

CLC Number: