幼猪深低温体外循环流量和预充液的改进

实验动物与比较医学 ›› 1999, Vol. 19 ›› Issue (3): 152-155.

幼猪深低温体外循环流量和预充液的改进

上海第二医科大学附属新华医院小儿心胸外科，上海 200092

收稿日期:1998-07-12 出版日期:1999-01-25 发布日期:2013-03-19

"Modification on Perfusion Flow Rate and Prime Formula under Deep Hypothermic Cardiopulmonary Bypass in Piglet "

Received:1998-07-12 Published:1999-01-25 Online:2013-03-19

摘要/Abstract

摘要： 利用幼猪复制深低温体外循环模型，研究2种流量和2种预充液配方对幼猪体温变化速率、体液平衡以及转流液中红细胞压积和胶体渗透压的影响。结果表明80ml·kg^-1·min^-1的流量以及全血预充液明显优于100ml·kg^-1·min^-1的流量和晶胶混和预充液。提示深低温体外循环的动物实验模型应根据所选动物生理情况正确设计流量和预充液配方。

关键词: 深低温体外循环, 预充液, 流量, 幼猪

Abstract: "Deep hypothermic cardiopulmonary bypass (DHCPB) model was established in piglets. Two grades of perfusion flow rate and two types of prime formula were used to study their influnce on changing rate of body temperature, balance of body fluid，blood hematocrit and colloidal pressure in prime. The results showed that 80ml • kg^-1• min^-1 of perfusion flow rate and pure blood prime were better than 100ml • kg^-1• min^-1 and mixed prime of crystalloid and blood. The results suggested that perfusion flow rate and prime formula should be correctly designed according to the normal physiology of selected animals when DHCPB model was to be established. "

Key words: "Deep hypothermic cardiopulmonary bypass, Prime, Perfusion flow rate, Piglet "

杨艳敏,陈恩,邹文艳,等. 幼猪深低温体外循环流量和预充液的改进[J]. 实验动物与比较医学, 1999, 19(3): 152-155.

YANG Yan-Min,CHEN 恩,ZOU Wen-Yan,et al. "Modification on Perfusion Flow Rate and Prime Formula under Deep Hypothermic Cardiopulmonary Bypass in Piglet "[J]. Laboratory Animal and Comparative Medicine, 1999, 19(3): 152-155.

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