昆明小鼠遗传特性形成过程探讨

›› 1994, Vol. 14 ›› Issue (1): 1-4.

所属专题：实验动物资源开发与利用

• 论文 • 下一篇

昆明小鼠遗传特性形成过程探讨

中国科学院上海实验动物中心

收稿日期:1993-11-08 出版日期:1994-01-25 发布日期:1994-01-25

Probing into the Course of Formation of Genetic Character of KM Mouse

Shanghai Laboratory Animal Center, Academia Sinica,Shanghai 200233

Received:1993-11-08 Online:1994-01-25 Published:1994-01-25

摘要/Abstract

摘要： 采用同工酶电泳法、微量细胞毒法及形态分析法，测定了40只昆明（KM）小鼠、30只云南小家鼠（Mus musculus castaneus）的遗传特性，并与西欧小家鼠（Mus musculus domesticus）进行了比较。结果显示：KM小鼠与M.m.domesticus的颧骨板形态相吻合，两者的遗传概貌基本一致。KM小鼠和云南小家鼠虽均含有M.m.domesticus所没有的Thy-1^a、Es-2^c基因型，但KM小鼠与M.m.domesticus的遗传距离较近，为0.2631，与云南小家鼠的遗传距离较远，为0.6165。作者据此推测，KM小鼠起源于西欧M.m.domesticus，其原种被引入我国云南省后，与M.m.castaneus发生过父源性遗传污染，有少量遗传物质侵入该群体。

关键词: 昆明小鼠, 小家鼠, 遗传概貌, 颧骨板

Abstract: Through isoenzyme electrophoresis,microcytotoxity test and morphological analysis, the genetic characters and morphological features of 40 KM mice and 30 wild mice （Mus musculus castaneus） from Yunnan province of China were investigated, and compared with the wild mouse（Mus musculus domesticus） from western Europe. The results indicated： KM mouse was similar to M.m. domesticus in genetic profile. Both were identical in the shape of the zygomatic plate. Though KM mouse and Yunnan wild mouse contain Thy-1^a and Es-2^C which were lacking in M. m. domesticus, the genetic distance between KM mouse and M. m. domesticus was 0.2631，while it was 0.6165 between KM mouse and Yunnan wild mouse.The results suggested that KM mouse was originated from western Europe wild mouse （M. m. domesticus） and was genetically contaminated by M. m. castaneus after introduced into Yunnan province.

Key words: KM mouse, Mus musculus, Genetic profile, Zygomatic plate

赵国际, 鲍世民, 张德福, 张瑞忠, 金玫蕾. 昆明小鼠遗传特性形成过程探讨[J]. , 1994, 14(1): 1-4.

ZHAO Guo-Ji, BAO Shi-Min, ZHANG De-Fu, ZHANG Rui-Zhong, JIN Mei-Lei. Probing into the Course of Formation of Genetic Character of KM Mouse[J]. , 1994, 14(1): 1-4.

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昆明小鼠遗传特性形成过程探讨

Probing into the Course of Formation of Genetic Character of KM Mouse

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